What causes chronic wasting disease?
Chronic wasting disease is caused by a misfolded protein called a prion. All mammals produce normal prions that are used by cells, then degraded and eliminated, or recycled, within the body. When disease-associated prions contact normal prions, they cause them to refold into their own abnormal shape. These disease-associated prions are not readily broken down and tend to accumulate in--and damage--lymphatic and neural tissues, including the brain.
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What are the visual signs of chronic wasting disease?
What is chronic wasting disease?
Chronic wasting disease—Research by the U.S. Geological Survey and partners
IntroductionChronic wasting disease (CWD) is the only transmissible spongiform encephalopathy, a class of invariably fatal neurodegenerative mammalian diseases associated with a misfolded cellular prion protein found in wild free-ranging animals. Because it has a long incubation period, affected animals in Cervidae (the deer family; referred to as...
Hopkins, M. Camille; Carlson, Christina M.; Cross, Paul C.; Johnson, Christopher J.; Richards, Bryan J.; Russell, Robin E.; Samuel, Michael D.; Sargeant, Glen A.; Walsh, Daniel P.; Walter, W. David
U.S. Geological Survey response to chronic wasting disease
The U.S. Geological Survey (USGS) is focused on the development of early detection and effective response tools that promote an adaptive management approach to chronic wasting disease (CWD). USGS scientists across the United States are working to understand the biology of CWD, assess and predict the spread and persistence in wildlife and the...
Hopkins, M. Camille; Soileau, Suzanna C.
Chronic wasting disease—Status, science, and management support by the U.S. Geological Survey
The U.S. Geological Survey (USGS) investigates chronic wasting disease (CWD) at multiple science centers and cooperative research units across the Nation and supports the management of CWD through science-based strategies. CWD research conducted by USGS scientists has three strategies: (1) to understand the biology, ecology, and causes and...
Carlson, Christina M.; Hopkins, M. Camille ; Nguyen, Natalie T.; Richards, Bryan J.; Walsh, Daniel P.; Walter, W. David
Field Manual of Wildlife Diseases
Welcome to a new version of the “Field Manual of Wildlife Diseases.” Unlike the previous printed versions of this publication, this new version is being developed as a “living“ electronic publication. Content will periodically be added and (or) updated as warranted, and it will always be reviewed by scientific experts (...
Franson, J. Christian; Friend, Milton; Gibbs, Samantha E. J.; Wild, Margaret A.
Why bother about wildlife disease?
In most developed countries, the maintenance of the numbers of wildlife1 is vested in the natural resource agencies of those countries. During earlier times, game species were the primary focus of natural resource agencies2,3 however, current wildlife conservation continues to transition towards a more holistic focus on biodiversity4...
Friend, Milton
Enhanced surveillance strategies for detecting and monitoring chronic wasting disease in free-ranging cervids
The purpose of this document is to provide wildlife management agencies with the foundation upon which they can build scientifically rigorous and cost-effective surveillance and monitoring programs for chronic wasting disease (CWD) or refine their existing programs. The first chapter provides an overview of potential demographic and spatial risk...
Walsh, Daniel P.
Chronic Wasting Disease
Chronic wasting disease (CWD) is an always-fatal, neurological illness occurring in North American cervids (members of the deer family), including white-tailed deer, mule deer, elk and moose. Since its discovery in 1967, CWD has spread geographically and increased in prevalence locally. CWD is contagious; it can be transmitted freely within and...
Richards, Bryan
Chronic Wasting Disease Positive Tissue Bank
In 2005, the USGS National Wildlife Health Center entered into an agreement with the Wyoming Game and Fish Department and the Department of Veterinary Sciences at the University of Wyoming to produce a collection of positive tissues from cervids intentionally infected with chronic wasting disease. This agreement was facilitated through the...
Wright, Scott D.
Disease emergence and resurgence—the wildlife-human connection
In 2000, the Global Outbreak Alert and Response Network (GOARN) was organized as a global disease watchdog group to coordinate disease outbreak information and health crisis response. The World Health Organization (WHO) is the headquarters for this network. Understandably, the primary focus for WHO is human health. However, diseases such as the...
Friend, Milton; Hurley, James W.; Nol, Pauline; Wesenberg, Katherine
Is this safe to eat?: Chapter 5 in Disease emergence and resurgence: The wildlife-human connection
The harvest and consumption of wildlife is as old as humankind and often has sustained human exploration into unsettled areas. Wildlife still remain a primary foodbase for many native peoples throughout the world. From shellfish to bear, humans today continue to hunt, fish, and otherwise harvest wildlife for recreation, social and cultural needs,...
Nol, Pauline; Friend, Milton
New Approach May Detect Chronic Wasting Disease Earlier, at Less Cost
A new statistical approach to disease surveillance may improve scientists’ and managers’ ability to detect chronic wasting disease earlier in white-tailed deer by targeting higher-risk animals. This approach can also provide financial and personnel savings for agencies that are required to monitor for wildlife diseases, including the National Park Service, or NPS.
Chronic Wasting Disease in White-Tailed Deer
Chronic wasting disease may have long-term negative effects on white-tailed deer, a highly visible and economically valuable keystone species, according to a new study from the USGS and published in Ecology.
Environmental Persistence of Chronic Wasting Disease Exacerbates Deer Population Declines
Long-term impacts of the chronic wasting disease (CWD) epidemic in North American deer, elk and moose will depend on how the disease persists in the environment, according to a new U.S. Geological Survey study.
Lichens May Aid in Combating Deadly Chronic Wasting Disease in Wildlife
Certain lichens can break down the infectious proteins responsible for chronic wasting disease (CWD), a troubling neurological disease fatal to wild deer and elk and spreading throughout the United States and Canada, according to U.S. Geological Survey research published today in the journal PLoS ONE.
Distribution of Chronic Wasting Disease in North America
Distribution of Chronic Wasting Disease in North America, updated September 4, 2020.
Mule Deer
A female mule deer in Texas, quite far from its type location. Credit: Alex Demas, USGS.
A bull elk with chronic wasting disease
A bull elk with chronic wasting disease at Wind Cave National Park. The emaciated appearance and drooping ears are characteristic of latter stages of infection.
Disease Detectives: Investigating the Mysteries of Zoonotic Diseases
Zoonotic diseases are those that are spread between wildlife and humans, and are an increasing health threat in the U.S. and throughout the world. As such diseases emerge, scientists with the U.S. Geological Survey and other wildlife health agencies must embark upon complex investigative work to determine what these diseases are, where they come from, and how they’re
Deer with Chronic Wasting Disease
This deer shows visible signs of chronic wasting disease.