Department of Defense Lung Study Active
Between 2003 and the present, 2.2 million U.S. military personnel have been deployed to Iraq and Afghanistan. These deployers have been variably exposed to desert dusts, smoke from burn pits, and urban particulate matter, and some have developed constrictive bronchiolitis. A study was undertaken to determine what, if any, markers were statistically different among biopsied lung tissue sections collected from deployed service members, a normal age- and smoking-matched control group, and an autoimmune control group. The laboratory has designed a method to characterize particulate matter in situ in biopsied lung tissue using scanning electron microscopy and energy dispersive spectroscopy. Presently we are designing an experiment to test the accuracy of the in situ measurements by comparing to bulk measurements of particulate matter in the lung.
Below are publications associated with this project.
Method to characterize inorganic particulates in lung tissue biopsies using field emission scanning electron microscopy
Below are news stories associated with this project.
Below are partners associated with this project.
- Overview
Between 2003 and the present, 2.2 million U.S. military personnel have been deployed to Iraq and Afghanistan. These deployers have been variably exposed to desert dusts, smoke from burn pits, and urban particulate matter, and some have developed constrictive bronchiolitis. A study was undertaken to determine what, if any, markers were statistically different among biopsied lung tissue sections collected from deployed service members, a normal age- and smoking-matched control group, and an autoimmune control group. The laboratory has designed a method to characterize particulate matter in situ in biopsied lung tissue using scanning electron microscopy and energy dispersive spectroscopy. Presently we are designing an experiment to test the accuracy of the in situ measurements by comparing to bulk measurements of particulate matter in the lung.
- Publications
Below are publications associated with this project.
Method to characterize inorganic particulates in lung tissue biopsies using field emission scanning electron microscopy
Humans accumulate large numbers of inorganic particles in their lungs over a lifetime. Whether this causes or contributes to debilitating disease over a normal lifespan depends on the type and concentration of the particles. We developed and tested a protocol for in situ characterization of the types and distribution of inorganic particles in biopsied lung tissue from three human groups using fielAuthorsHeather A. Lowers, George N. Breit, Matthew Strand, Renee M. Pillers, Gregory P. Meeker, Todor I. Todorov, Geoffrey S. Plumlee, Ruth E. Wolf, Maura Robinson, Jane Parr, Robert J. Miller, Steve Groshong, Francis Green, Cecile Rose - News
Below are news stories associated with this project.
- Partners
Below are partners associated with this project.