Barnett Rattner, Ph.D.
Dr. Barnett Rattner is an ecotoxicologist at the Eastern Ecological Science Center in Laurel, MD.
He conducts hypothesis-driven laboratory and field investigations, risk assessments and scholarly evaluations on the toxicity of legacy and contemporary pollutants (industrial contaminants, metals, pesticides, petroleum crude oil) to wildlife and the environment. His current focus is on exposure and adverse effects of anticoagulant rodenticides, flame retardants and pharmaceuticals, comparative toxicology, non-target secondary poisoning associated with rodenticides, alternative testing methods, and screening-level risk assessments. Dr. Rattner actively represents the DOI as a member of the Interagency Coordinating Committee on the Validation of Alternative Methods, and serves as a special consultant to the Fish and Wildlife Service on issues related to nontoxic shot used in hunt nontoxic shot used in hunt waterfowl.
Active Projects:
- Development of data and models to evaluate the hazard and risk of anticoagulant rodenticides to non-target raptorial species
- Absorption, distribution, metabolism, elimination and toxicity of neonicotinoids in seed-eating birds
- Harmful algal blooms and bird die-offs in the Chesapeake Bay: A potential link?
- Contaminant exposure and potential reproductive effects in ospreys nesting in Chesapeake and Delaware Bay
- Contaminant-related activities and synoptic reviews in support of client agencies in the Department of the Interior
- Technical assistance to the Fish and Wildlife Service on alternative shot
Accomplishments:
- Authored over 135 publications, co-edited three books (Handbook of Ecotoxicology, Ecotoxicology of Wild Mammals, Anticoagulant Rodenticides and Wildlife), and made over 160 presentations at scientific meetings, workshops and symposia.
- Compiled two widely used internet-accessible ecotoxicological databases (Contaminant Exposure and Effects—Terrestrial Vertebrates database, Biological and Ecotoxicological Characteristics of Terrestrial Vertebrate Species Residing in Estuaries).
- Serves as Terrestrial Editor of Environmental Toxicology and Chemistry, and as an Editorial Board member of the Bulletin of Environmental Contamination and Toxicology, and Outlooks on Pest Management.
Professional Experience
Ecotoxicologist and Physiologist (research scientist, section leader, deputy branch chief) Department of the Interior, FWS, NBS, and USGS (1978-present)
Adjunct Professor University of Maryland, Department of Animal and Avian Sciences & Department of Environmental Science and Technology (1988-2022)
National Research Council Post-doctoral Research Associate, National Naval Medical Center (1978
Guest Worker, National Institute of Arthritis, Metabolism and Digestive and Kidney Diseases, NIH (1974-1981)
Instructor and Graduate Teaching Assistant, University of Maryland, Department of Zoology (1972-1977)
Education and Certifications
B.S., University of Maryland, 1972 - Zoology
M.S., University of Maryland, 1974 - Zoology, Developmental Biology
Ph.D., University of Maryland, 1977 - Zoology, Environmental Physiology
National Research Council Postdoctoral Associateship, Naval Medical Research Institute, 1978 - Hyperbaric Physiology
Affiliations and Memberships*
Society of Environmental Toxicology and Chemistry
Society of Toxicology
The Wildlife Society
American Physiological Society
Honors and Awards
Distinguished Service Award, Department of the Interior 2018
Fellow, Society of Environmental Toxicology and Chemistry 2017
President, Society of Environmental Toxicology and Chemistry World Council 2015
President, Society of Environmental Toxicology and Chemistry - North America 2012
SETAC Government Service Award 2007
Science and Products
Interactive effects of climate change with nutrients, mercury, and freshwater acidification on key taxa in the North Atlantic Landscape Conservation Cooperative region
Exposure and food web transfer of pharmaceuticals in ospreys (Pandion haliaetus): Predictive model and empirical data
Decadal re-evaluation of contaminant exposure and productivity of ospreys (Pandion haliaetus) nesting in Chesapeake Bay Regions of Concern
Toxicity reference values for chlorophacinone and their application for assessing anticoagulant rodenticide risk to raptors
Investigating endocrine and physiological parameters of captive American kestrels exposed by diet to selected organophosphate flame retardants
Changes in thyroid parameters of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short chain chlorinated paraffins (SCCPs; C10-13, 55.5% CL)
Adverse outcome pathway and risks of anticoagulant rodenticides to predatory wildlife
Toxicity of Pb-contaminated soil to Japanese quail (Coturnix japonica) and the use of the blood-dietary Pb slope in risk assessment
Development of dietary-based toxic reference values to assess the risk of chlorophacinone to non-target raptorial birds
Toxicokinetics and coagulopathy threshold of the rodenticide diphacinone in eastern screech-owls (Megascops asio)
Comparative embryotoxicity of a pentabrominated diphenyl ether mixture to common terns (Sterna hirundo) and American kestrels (Falco sparverius)
Toxic exposure of songbirds to lead in the Southeast Missouri Lead Mining District
Science and Products
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Interactive effects of climate change with nutrients, mercury, and freshwater acidification on key taxa in the North Atlantic Landscape Conservation Cooperative region
The North Atlantic Landscape Conservation Cooperative LCC (NA LCC) is a public–private partnership that provides information to support conservation decisions that may be affected by global climate change (GCC) and other threats. The NA LCC region extends from southeast Virginia to the Canadian Maritime Provinces. Within this region, the US National Climate Assessment documented increases in air tAuthorsAlfred E. Pinkney, Charles T. Driscoll, David C. Evers, Michael J. Hooper, Jeffrey Horan, Jess W. Jones, Rebecca S. Lazarus, Harold G. Marshall, Andrew Milliken, Barnett A. Rattner, John J. Schmerfeld, Donald W. SparlingExposure and food web transfer of pharmaceuticals in ospreys (Pandion haliaetus): Predictive model and empirical data
The osprey (Pandion haliaetus) is a well-known sentinel of environmental contamination, yet no studies have traced pharmaceuticals through the water–fish–osprey food web. A screening-level exposure assessment was used to evaluate the bioaccumulation potential of 113 pharmaceuticals and metabolites, and an artificial sweetener in this food web. Hypothetical concentrations in water reflecting “wasteAuthorsRebecca S. Lazarus, Barnett A. Rattner, Bowen Du, Peter C. McGowan, Vicki S. Blazer, Mary Ann OttingerDecadal re-evaluation of contaminant exposure and productivity of ospreys (Pandion haliaetus) nesting in Chesapeake Bay Regions of Concern
The last large-scale ecotoxicological study of ospreys (Pandion haliaetus) in Chesapeake Bay was conducted in 2000-2001 and focused on U.S. EPA-designated Regions of Concern (ROCs; Baltimore Harbor/Patapsco, Anacostia/middle Potomac, and Elizabeth Rivers). In 2011-2012, ROCs were re-evaluated to determine spatial and temporal trends in productivity and contaminants. Concentrations of p,p'-DDE wereAuthorsRebecca S. Lazarus, Barnett A. Rattner, Peter C. McGowan, Robert C. Hale, Sandra L. Schultz, Natalie K. Karouna-Renier, Mary Ann OttingerToxicity reference values for chlorophacinone and their application for assessing anticoagulant rodenticide risk to raptors
Despite widespread use and benefit, there are growing concerns regarding hazards of second-generation anticoagulant rodenticides to non-target wildlife which may result in expanded use of first-generation compounds, including chlorophacinone (CPN). The toxicity of CPN over a 7-day exposure period was investigated in American kestrels (Falco sparverius) fed either rat tissue mechanically-amended wiAuthorsBarnett A. Rattner, Katherine E. Horak, Rebecca S. Lazarus, Sandra L. Schultz, Susan Knowles, Benjamin G. Abbo, Steven F. VolkerInvestigating endocrine and physiological parameters of captive American kestrels exposed by diet to selected organophosphate flame retardants
Organophosphate triesters are high production volume additive flame retardants (OPFRs) and plasticizers. Shown to accumulate in abiotic and biotic environmental compartments, little is known about the risks they pose. Captive adult male American kestrels (Falco sparverius) were fed the same dose (22 ng OPFR/g kestrel/d) daily (21 d) of tris(2- butoxyethyl) phosphate (TBOEP), tris(2-chloroethyl) phAuthorsKJ Fernie, V. Palace, L. Peters, Niladri Basu, R.J. Letcher, Natalie K. Karouna-Renier, Sandra L. Schultz, Rebecca S. Lazarus, Barnett A. RattnerChanges in thyroid parameters of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short chain chlorinated paraffins (SCCPs; C10-13, 55.5% CL)
Chlorinated paraffins (CPs) are complex mixtures of polychlorinated n-alkanes categorized according to their carbon chain length: short chain (SCCPs, C10 – C13), medium (C14 - C17), and long chain (C>17), chlorinated paraffins. SCCPs are primarily used in metalworking applications, as flame retardants, and in paints, adhesives, sealants, textiles, plastics and rubber (UNEP 2012). In 2012, the UnitAuthorsKimberly J. Fernie, Paula F. P. Henry, Robert J. Letcher, Vince P. Palace, Lisa E. Peters, Barnett A. Rattner, Edward Sverko, Natalie K. Karouna-RenierAdverse outcome pathway and risks of anticoagulant rodenticides to predatory wildlife
Despite a long history of successful use, routine application of some anticoagulant rodenticides (ARs) may be at a crossroad due to new regulatory guidelines intended to mitigate risk. An adverse outcome pathway for ARs was developed to identify information gaps and end points to assess the effectiveness of regulations. This framework describes chemical properties of ARs, established macromoleculaAuthorsBarnett A. Rattner, Rebecca S. Lazarus, John E. Elliott, Richard F. Shore, Nico van den BrinkToxicity of Pb-contaminated soil to Japanese quail (Coturnix japonica) and the use of the blood-dietary Pb slope in risk assessment
This study relates tissue concentrations and toxic effects of Pb in Japanese quail (Coturnix japonica) to the dietary exposure of soil-borne Pb associated with mining and smelting. From 0% to 12% contaminated soil, by weight, was added to 5 experimental diets (0.12 to 382 mg Pb/kg, dry wt) and fed to the quail for 6 weeks. Benchmark doses associated with a 50% reduction in delta-aminolevulinic aciAuthorsW. Nelson Beyer, Yu Chen, Paula Henry, Thomas May, David Mosby, Barnett A. Rattner, Valerie I. Shearn-Bochsler, Daniel Sprague, John WeberDevelopment of dietary-based toxic reference values to assess the risk of chlorophacinone to non-target raptorial birds
Regulatory changes in the use of some second-generation anticoagulant rodenticides in parts of North America may result in expanded use of first-generation anticoagulant rodenticides (FGARs). Recent toxicological studies with captive raptors have demonstrated that these species are considerably more sensitive to the FGAR diphacinone than traditional avian wildlife test species (mallard, bobwhite).AuthorsBarnett A. Rattner, Rebecca S. Lazarus, S. L. Shultz, Katherine E. Horak, Benjamin G. Abbo, Steven F. VolkerToxicokinetics and coagulopathy threshold of the rodenticide diphacinone in eastern screech-owls (Megascops asio)
In the United States, new regulations on second-generation anticoagulant rodenticides will likely be offset by expanded use of first-generation anticoagulant rodenticides. In the present study, eastern screech-owls (Megascops asio) were fed 10 µg diphacinone/g wet weight food for 7 d, and recovery was monitored over a 21-d postexposure period. By day 3 of exposure, diphacinone (DPN) was detected iAuthorsBarnett A. Rattner, K.E. Horak, Rebecca S. Lazarus, D.A. Goldade, J. J. JohnstonComparative embryotoxicity of a pentabrominated diphenyl ether mixture to common terns (Sterna hirundo) and American kestrels (Falco sparverius)
Concentrations of polybrominated diphenyl ethers (PBDEs) in Forster’s tern (Sterna forsteri) eggs from San Francisco Bay have been reported to range up to 63 μg g−1 lipid weight. This value exceeds the lowest-observed-adverse-effect level (1.8 μg g−1 egg wet weight; ∼32 μg−1 lipid weight) reported in an embryotoxicity study with American kestrels (Falco sparverius). As a surrogate for Forster’s teAuthorsBarnett A. Rattner, Rebecca S. Lazarus, Gary H. Heinz, Natalie K. Karouna-Reiner, Sandra L. Schultz, Robert C. HaleToxic exposure of songbirds to lead in the Southeast Missouri Lead Mining District
Mining and smelting in the Southeast Missouri Lead Mining District has caused widespread contamination of soils with lead (Pb) and other metals. Soils from three study sites sampled in the district contained from approximately 1,000–3,200 mg Pb/kg. Analyses of earthworms [33–4,600 mg Pb/kg dry weight (dw)] collected in the district showed likely high Pb exposure of songbirds preying on soil organiAuthorsW. Nelson Beyer, J. Christian Franson, John B. French, Thomas May, Barnett A. Rattner, Valerie I. Shearn-Bochsler, Sarah E. Warner, John Weber, David Mosby - Web Tools
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*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government