Dana W Kolpin
Dana Kolpin is a Research Hydrologist, with the Central Midwest Water Science Center in Iowa City, Iowa. Dana started his career with the USGS in 1984. His research interests include the fate, transport, and effects of environmental contaminants (e.g. pesticides, human and veterinary pharmaceuticals, hormones, etc.) in the environment.
Dana was the project lead of the USGS Toxic Program’s CECs in the Environment Project for its entire history (1998 – 2017). He is now project lead of the USGS Toxic Program’s newly formed Food Project (i.e. understanding the potential for health risks from contaminant exposures associated with production, manufacturing, use, and consumption of food, beverage, and feedstock products). He has published over 200 papers and reports on environmental contaminants. His paper "Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A national reconnaissance" was a seminal paper on the occurrence of CECs in water resources, and was the first national-scale study of such compounds conducted in the United States. This paper has become the most heavily cited paper in Environmental Science & Technology history. He has published a diverse array of papers on the topic of environmental contaminants including research on CECs in landfills, changes in stream water chemistry and hydrology related to the closure of a wastewater treatment plant, detection of swine hepatitis E virus in streams, the transport of neonicotinoid insecticides in streams, the uptake of CECs into earthworms and into fish neural tissue, the occurrence of natural toxins (i.e. phytoestrogens and mycotoxins) in streams, and the first ever documentation of the off-field transport on nitrapyrin and herbicide safeners to streams. His most recent research interests include linking tap water quality to human health end points, investigating PFAS exposures in rural settings, determining the prevalence of antibiotic resistance genes in the environment, and understanding chemical and microbial contaminants being discharged into the environment by food and feedstock processing plants.
Education and Certifications
M.S., Geology, University of Iowa, Iowa City, Iowa
B.S., Geology, Iowa State University, Ames, Iowa
Science and Products
Widespread use of the nitrification inhibitor nitrapyrin: Assessing benefits and costs to agriculture, ecosystems, and environmental health
Groundwater discharges as a source of phytoestrogens and other agriculturally derived contaminants to streams
Occurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures
Poultry litter as potential source of pathogens and other contaminants in groundwater and surface water proximal to large-scale confined poultry feeding operations
Polymeric nanofiber-carbon nanotube composite mats as fast-equilibrium passive samplers for polar organic pollutants
A critical review on the potential impacts of neonicotinoid insecticide use: Current knowledge of environmental fate, toxicity, and implications for human health
Landfill leachate contributes per-/poly-fluoroalkyl substances (PFAS) and pharmaceuticals to municipal wastewater
Mixed organic and inorganic tapwater exposures and potential effects in greater Chicago area, USA
De facto water reuse: Bioassay suite approach delivers depth and breadth in endocrine active compound detection
Urban stormwater: An overlooked pathway of extensive mixed contaminants to surface and groundwaters in the United States
Predictive analysis using chemical-gene interaction networks consistent with observed endocrine activity and mutagenicity of U.S. streams
Chlorinated byproducts of neonicotinoids and their metabolites: An unrecognized human exposure potential?
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Widespread use of the nitrification inhibitor nitrapyrin: Assessing benefits and costs to agriculture, ecosystems, and environmental health
Agricultural production and associated applications of nitrogen (N) fertilizers have increased dramatically in the last century, and current projections to 2050 show that demands will continue to increase as the human population grows. Applied in both organic and inorganic fertilizer forms, N is an essential nutrient in crop productivity. Increased fertilizer applications, however, create the poteAuthorsEmily Woodward, Thea Margaret Edwards, Carrie E Givens, Dana W. Kolpin, Michelle HladikGroundwater discharges as a source of phytoestrogens and other agriculturally derived contaminants to streams
Groundwater discharge zones in streams are important habitats for aquatic organisms. The use of discharge zones for thermal refuge and spawning by fish and other biota renders them susceptible to potential focused discharge of groundwater contamination. Currently, there is a paucity of information about discharge zones as a potential exposure pathway of chemicals to stream ecosystems. Using thermaAuthorsTyler J. Thompson, Martin A. Briggs, Patrick J. Phillips, Vicki S. Blazer, Kelly L. Smalling, Dana W. Kolpin, Tyler WagnerOccurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures
Effluent-dominated streams are becoming increasingly common in temperate regions and generate complex pharmaceutical mixture exposure conditions that may impact aquatic organisms via drug–drug interactions. Here, we quantified spatiotemporal pharmaceutical exposure concentrations and composition mixture dynamics during baseflow conditions at four sites in a temperate-region effluent-dominated streAuthorsHui Zhi, Dana W. Kolpin, R. D. Klaper, Luke R. Iwanowicz, Shannon M. Meppelink, Gregory H. LeFevrePoultry litter as potential source of pathogens and other contaminants in groundwater and surface water proximal to large-scale confined poultry feeding operations
Manure from livestock production has been associated with the contamination of water resources. To date, research has primarily focused on runoff of these contaminants from animal operations into surface water, and the introduction of poultry-derived pathogenic zoonoses and other contaminants into groundwater is under-investigated. We characterized pathogens and other microbial and chemical contamAuthorsLaura E. Hubbard, Carrie E. Givens, Dale W. Griffin, Luke Iwanowicz, Michael T. Meyer, Dana W. KolpinPolymeric nanofiber-carbon nanotube composite mats as fast-equilibrium passive samplers for polar organic pollutants
To improve the performance of polymeric electrospun nanofiber mats (ENMs) for equilibrium passive sampling applications in water, we integrated two types of multiwalled carbon nanotubes (CNTs; with and without surface carboxyl groups) into polyacrylonitrile (PAN) and polystyrene (PS) ENMs. For 11 polar and moderately hydrophobic compounds (−0.07 ≤ logKOW ≤ 3.13), 90% of equilibrium uptake was achiAuthorsJiajie Qian, Andres Martinez, Rachel F Marek, Matthew R. Nagorzanski, Hui Zhi, Edward Furlong, Dana W. Kolpin, Gregory H. LeFevre, David M. CwiertnyA critical review on the potential impacts of neonicotinoid insecticide use: Current knowledge of environmental fate, toxicity, and implications for human health
Neonicotinoid insecticides are widely used in both urban and agricultural settings around the world. Historically, neonicotinoid insecticides have been viewed as ideal replacements for more toxic compounds, like organophosphates, due in part to their perceived limited potential to affect the environment and human health. This critical review investigates the environmental fate and toxicity of neonAuthorsHans-Joachim Lehmler, Dana W. Kolpin, Michelle L. Hladik, John D. Vargo, Keith E. Schilling, Gregory H. LeFevre, Tonya L. Peeples, Matthew C. Poch, Lauren E. LaDuca, David M. Cwiertny, R. William FieldLandfill leachate contributes per-/poly-fluoroalkyl substances (PFAS) and pharmaceuticals to municipal wastewater
Widespread disposal of landfill leachate to municipal sewer infrastructure in the United States calls for an improved understanding of the relative organic-chemical contributions to the wastewater treatment plant (WWTP) waste stream and associated surface-water discharge to receptors in the environment. Landfill leachate, WWTP influent, and WWTP effluent samples were collected from three landfill-AuthorsJason R. Masoner, Dana W. Kolpin, Isabelle M. Cozzarelli, Kelly L. Smalling, Stephanie Bolyard, Jennifer Field, Edward T. Furlong, James L. Gray, Duncan Lozinski, Debra Reinhart, Alix Rodowa, Paul M. BradleyMixed organic and inorganic tapwater exposures and potential effects in greater Chicago area, USA
Safe drinking water at the point of use (tapwater, TW) is a public-health priority. TW exposures and potential human-health concerns of 540 organics and 35 inorganics were assessed in 45 Chicago area United States (US) homes in 2017. No US Environmental Protection Agency (EPA) enforceable Maximum Contaminant Level(s) (MCL) were exceeded in any residential or water treatment plant (WTP) pre-distribAuthorsPaul Bradley, Maria Argos, Dana W. Kolpin, Shannon M. Meppelink, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Joshua M. Allen, Julie E. Dietze, Michael J. Devito, Ariel Donovan, Nicola Evans, Carrie E. Givens, James L. Gray, Christopher P. Higgins, Michelle Hladik, Luke Iwanowicz, Celeste A. Journey, Rachael F. Lane, Zachary Laughrey, Keith A. Loftin, R. Blaine McCleskey, Carrie A. McDonough, Elizabeth K Medlock Kakaley, Michael T. Meyer, Andrea Holthouse-Putz, Susan D Richardson, Alan Stark, Christopher P. Weis, Vickie S. Wilson, Abderrahman ZehraouiDe facto water reuse: Bioassay suite approach delivers depth and breadth in endocrine active compound detection
Although endocrine disrupting compounds (EDCs) have been detected in wastewater and surface waters worldwide using a variety of in vitro effects-based screening tools, e.g. bioassays, few have examined potential attenuation of environmental contaminants by both natural (sorption, degradation, etc) and anthropogenic (water treatment practices) processes. This study used several bioassays and quantiAuthorsElizabeth K Medlock Kakaley, Brett R. Blackwell, Mary C. Cardon, Justin M. Conley, Nicola Evans, David J. Feifarek, Edward Furlong, Susan T. Glassmeyer, L. Earl Jr. Gray, Phillip C. Hartig, Dana W. Kolpin, Marc A. Mills, Laura Rosenblum, Daniel L. Villeneuve, Vickie S. WilsonUrban stormwater: An overlooked pathway of extensive mixed contaminants to surface and groundwaters in the United States
Increasing global reliance on stormwater control measures to reduce discharge to surface water, increase groundwater recharge, and minimize contaminant delivery to receiving waterbodies necessitates improved understanding of stormwater-contaminant profiles. A multi-agency study of organic and inorganic chemicals in urban stormwater from 50 runoff events at 21 sites across the United States demonstAuthorsJason R. Masoner, Dana W. Kolpin, Isabelle M. Cozzarelli, Larry B. Barber, D.S. Burden, William T. Foreman, Kenneth J. Forshay, Edward Furlong, Justin F. Groves, Michelle Hladik, Matthew E. Hopton, Jeanne B. Jaeschke, Steffanie H. Keefe, David Krabbenhoft, Richard Lowrance, Kristin Romanok, David L. Rus, William R. Selbig, Brad Williams, Paul BradleyByWater Resources Mission Area, Science Synthesis, Analysis and Research Program, Contaminant Biology, Science Analytics and Synthesis (SAS) Program, Toxic Substances Hydrology, California Water Science Center, Central Midwest Water Science Center, New Jersey Water Science Center, Oklahoma-Texas Water Science Center, South Atlantic Water Science Center (SAWSC), Upper Midwest Environmental Sciences Center, Upper Midwest Water Science Center, Reston Biogeochemical Processes in Groundwater LaboratoryPredictive analysis using chemical-gene interaction networks consistent with observed endocrine activity and mutagenicity of U.S. streams
In a recent U.S. Geological Survey/U.S. Environmental Protection Agency study assessing >700 organic compounds in 38 streams, in vitro assays indicated generally low estrogen, androgen, and glucocorticoid receptor activities, but identified 13 surface waters with 17β estradiol equivalent (E2Eq) activities greater than the 1 ng/L level of concern for feminization of male fish. Among the 36 samplesAuthorsJason P. Berninger, David M. DeMarini, Sarah H. Warren, Jane Ellen Simmons, Vickie S. Wilson, Justin M. Conley, Mikayla D. Armstrong, Dana W. Kolpin, Kathryn Kuivila, Timothy J. Reilly, Kristin M. Romanok, Daniel L. Villeneuve, Paul M. Bradley, Luke R. IwanowiczByEcosystems Mission Area, Water Resources Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Columbia Environmental Research Center, Eastern Ecological Science Center, New Jersey Water Science Center, Pennsylvania Water Science Center, South Atlantic Water Science Center (SAWSC)Chlorinated byproducts of neonicotinoids and their metabolites: An unrecognized human exposure potential?
We recently reported the initial discovery of neonicotinoid pesticides in drinking water and their potential for transformation through chlorination and alkaline hydrolysis during water treatment. The objectives of this research were: (1) to determine if neonicotinoid metabolites are relevant to drinking water exposure and (2) to identify the products formed from chlorination of neonicotinoids andAuthorsKathryn L. Klarich Wong, Danielle T. Webb, Matthew R. Nagorzanski, Dana W. Kolpin, Michelle L. Hladik, David M. Cwiertny, Gregory H. LeFevre - News