Jeffrey S Hall
Biography
Education
2001 Doctor of Philosophy, Comparative Pathobiology, University of Nebraska-Lincoln, Lincoln, NE
Professional Experience
Sept. 2007 - Present Research Virologist USGS-NWHC, Madison, WI
Sept. 2003 - Sept. 2007 Virologist/ Laboratory Manager USDA-APHIS-NWRC. Ft. Collins, CO
July 1997 - Sept. 2003 Microbiologist USDA-ARS. Lincoln, NE
March 1991 - July 1997 Research Associate Department of Plant Pathology. University of Nebraska-Lincoln, Lincoln, NE
Science and Products
Avian Influenza
Avian influenza is a viral disease caused by various strains of avian influenza viruses that can be classified as low pathogenic avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). It remains a global disease with potential high consequence with the potential to threaten wildlife, agriculture, and human health.
Vector-Borne Diseases
Vector-borne diseases are transmitted from one animal to another by vectors, including insects, such as mosquitoes or fleas, and arachnids, such as ticks. The USGS National Wildlife Health Center investigates wildlife diseases, including vector-borne diseases, such as West Nile virus and sylvatic plague.
Experimental challenge of a North American bat species, big brown bat (Eptesicus fuscus), with SARS-CoV-2
The recently emerged novel coronavirus, SARS‐CoV‐2, is phylogenetically related to bat coronaviruses (CoVs), specifically SARS‐related CoVs from the Eurasian bat family Rhinolophidae. As this human pandemic virus has spread across the world, the potential impacts of SARS‐CoV‐2 on native North American bat populations are unknown, as is the ability...
Hall, Jeffrey S.; Knowles, Susan; Nashold, Sean; Ip, Hon S.; Leon, Ariel Elizabeth; Rocke, Tonie E.; Keller, Saskia Annatina; Carossino, Mariano; Balasuriya, Udeni B.R.; Hofmeister, Erik K.Serosurvey of coyotes (Canis latrans), foxes (Vulpes vulpes, Urocyon cinereoargenteus) and raccoons (Procyon lotor) for exposure to influenza A viruses in the USA
We tested coyote (Canis latrans), fox (Urocyon cinereoargenteus, Vulpes vulpes), and raccoon (Procyon lotor) sera for influenza A virus (IAV) exposure. We found 2/139 samples (1 coyote, 1 raccoon) had IAV antibodies and hemagglutination inhibition assays revealed the antibodies to the 2009/2010 H1N1 human pandemic virus or to the 2007 human...
Bakken, Marit A.; Nashold, Sean; Hall, Jeffrey S.Inactivation of viable surrogates for the select agents virulent Newcastle disease virus and highly pathogenic avian influenza virus using either commercial lysis buffer or heat
Introduction:Federal Select Agent Program regulations require laboratories to document a validated procedure for inactivating select agents prior to movement outside registered space. Avian influenza viruses and virulent Newcastle disease virus (vNDV) are cultured in chicken amnio-allantoic fluid (AAF), but the efficacy of commercial lysis buffers...
Alger, Katrina Elizabeth; Ip, Hon S.; Hall, Jeffrey S.; Nashold, Sean; Richgels, Katherine; Smith, Carrie AlisonAvian influenza virus prevalence in marine birds is dependent on ocean temperatures
Waterfowl and shorebirds are the primary hosts of influenza A virus (IAV), however, in most surveillance efforts, large populations of birds are not routinely examined; specifically marine ducks and other birds that reside predominately on or near the ocean. We conducted a long-term study sampling sea ducks and gulls in coastal Maine for IAV and...
Hall, Jeffrey S.; Dusek, Robert J.; Nashold, Sean; TeSlaa, Joshua L.; Allen, Bradford R.; Grear, Daniel A.Aerosol transmission of gull-origin Iceland subtype H10N7 influenza A virus in ferrets
Subtype H10 influenza A viruses (IAVs) have been recovered from domestic poultry and various aquatic bird species, and sporadic transmission of these IAVs from avian species to mammals (i.e., human, seal, and mink) are well documented. In 2015, we isolated four H10N7 viruses from gulls in Iceland. Genomic analyses showed four gene segments in the...
Guan, Minhui; Hall, Jeffrey S.; Zhang, Xiaojian; Dusek, Robert J.; Olivier, Alicia K.; Liu, Liyuan; Li, Lei; Krauss, Scott; Danner, Angea; Li, Tao; Rutvisuttinunt, Wiriya; Lin, Xiaoxu; Hallgrimsson, Gunnar T.; Ragnarsdottir, Sunna B.; Vignisson, Solvi R.; TeSlaa, Josh; Nashold, Sean; Jarman, Richard; Wan, Xiu-FengInfluenza A virus recovery, diversity, and intercontinental exchange: A multi-year assessment of wild bird sampling at Izembek National Wildlife Refuge, Alaska
Western Alaska is a potential point-of-entry for foreign-origin influenza A viruses (IAVs) into North America via migratory birds. We sampled waterfowl and gulls for IAVs at Izembek National Wildlife Refuge (NWR) in western Alaska, USA, during late summer and autumn months of 2011–2015, to evaluate the abundance and diversity of viruses at this...
Reeves, Andrew B.; Hall, Jeffery S.; Poulson, Rebecca L.; Donnelly, Tyrone F.; Stallknecht, David E.; Ramey, Andrew M.Infectious canine hepatitis in a brown bear (Ursus arctos horribilis) from Alaska.
We diagnosed infectious canine hepatitis in a free-ranging brown bear (Ursus arctos horribilis) cub from Alaska, US, found dead in October 2015. Intranuclear inclusion bodies were present in hepatocytes, and immunohistochemistry showed reactivity to adenoviral antigens. Sequencing of the hexon protein of adenovirus showed 100% identity to canine...
Knowles, Susan; Bodenstein, Barbara; Hamon, Troy; Saxton, Michael W.; Hall, Jeffrey S.Inferring epidemiologic dynamics from viral evolution: 2014–2015 Eurasian/North American highly pathogenic avian influenza viruses exceed transmission threshold, R0 = 1, in wild birds and poultry in North America
Highly pathogenic avian influenza virus (HPAIV) is a multihost pathogen with lineages that pose health risks for domestic birds, wild birds, and humans. One mechanism of intercontinental HPAIV spread is through wild bird reservoirs, and wild birds were the likely sources of a Eurasian (EA) lineage HPAIV into North America in 2014. The introduction...
Grear, Daniel R.; Hall, Jeffrey S.; Dusek, Robert J.; Ip, Hon S.Experimental infection of common eider ducklings with Wellfleet Bay virus, a newly characterized orthomyxovirus
Wellfleet Bay virus (WFBV), a novel orthomyxovirus in the genus Quaranjavirus, was first isolated in 2006 from carcasses of common eider (Somateria mollissima) during a mortality event in Wellfleet Bay (Barnstable County, Massachusetts, USA) and has since been repeatedly isolated during recurrent mortality events in this location. Hepatic,...
Shearn-Bochsler, Valerie I.; Ip, Hon S.; Ballmann, Anne; Hall, Jeffrey S.; Allison, Andrew B.; Ballard, Jennifer R.; Ellis, Julie C.; Cook, Robert; Gibbs, Samantha E. J.; Dwyer, Chris P.Lambdapapillomavirus 2 in a gray wolf (Canis lupus) from Minnesota with oral papillomatosis and sarcoptic mange
Oral papillomatosis was diagnosed in a gray wolf (Canis lupus) with sarcoptic mange from Minnesota, USA found dead in February 2015. Intranuclear inclusion bodies were evident histologically, and papillomaviral antigens were confirmed using immunohistochemistry. Sequencing of the L1 papillomavirus gene showed closest similarity to...
Knowles, Susan; Windels, Steve K.; Adams, Marie; Hall, Jeffrey S.Prevalence and distribution of Wellfleet Bay virus exposure in the Common Eider (Somateria mollissima)
Between 1998 and 2014, recurrent mortality events were reported in the Dresser's subspecies of the Common Eider (Somateria mollissima dresseri) on Cape Cod, Massachusetts, USA near Wellfleet Harbor. The early die-offs were attributed to parasitism and emaciation, but beginning in 2006 a suite of distinct lesions was observed concomitant with the...
Ballard, Jennifer R.; Mickley, Randall M.; Gibbs, Samantha E. J.; Dwyer, Chris P.; Soos, Catherine; Harms, N. Jane; Gilchrist, H. Grant; Hall, Jeffrey S.; Franson, J. Christian; Milton, G. Randy; Parsons, Glen; Allen, Brad; Giroux, Jean-Francois; Lair, Stéphane; Mead, Daniel G.; Fischer, John R.No evidence of infection or exposure to Highly Pathogenic Avian Influenzas in peridomestic wildlife on an affected poultry facility
We evaluated the potential transmission of avian influenza viruses (AIV) in wildlife species in three settings in association with an outbreak at a poultry facility: 1) small birds and small mammals on a poultry facility that was affected with highly pathogenic AIV (HPAIV) in April 2015; 2) small birds and small mammals on a nearby poultry...
Grear, Daniel A.; Dusek, Robert J.; Walsh, Daniel P.; Hall, Jeffrey S.