William N Batts
Bill loves to identify new fish viruses! Replicating viral agents are amplified by PCR and DNA sequenced to characterize the viruses. When novel viruses are found, he publishes manuscripts in scientific journals and presents findings at fish health conferences. Recently, Bill was an author on two chapters in the 2016 book, “Aquaculture Virology”.
Research Interests:
Research on all kinds of fish viruses. However, I am focused primarily on RNA viruses of fish. Provide technical assistance to fish health professionals whether they are from state, government, tribal, commercial or from other countries. Specialize in detection and identification methods for existing and novel viruses. I have studied a wide variety of virus types for genomic comparisons: IHNV, VHSV, and other rhabdoviruses of fish, paramyxoviruses, orthomyxoviruses, hepeviruses, nidoviruses, bunyaviruses, picornaviruses, reoviruses, birnaviruses, herpesviruses and iridoviruses. Have performed fish exposure studies to ascertain control and prevention strategies on fish viruses. Investigated various potential virus transmission modes. Overall, I'm just trying to understand how the various viruses do what they do and try to give the fish a better chance for survival.
Professional Experience
1983 to Present - Biologist, U.S. Geological Survey, Western Fisheries Research Center, Seattle, WA
Education and Certifications
M.S. 1990. Fisheries Sciences, University of Washington, Seattle, WA
B.S. 1983. Fisheries Sciences, University of Washington, Seattle, WA
Honors and Awards
2006 - Citation for the Most Significant Paper in the Journal of Aquatic Animal Health, Volume 18
1998 - Citation for the Most Significant Paper in the Journal of Aquatic Animal Health, Volume 9
1991 - Citation for the Most Significant Paper in the Journal of Aquatic Animal Health, Volume 2
Science and Products
Filter Total Items: 57
Molecular identification of erythrocytic necrosis virus (ENV) from the blood of Pacific herring (Clupea pallasii)
Viral erythrocytic necrosis (VEN) is a condition affecting the red blood cells of more than 20 species of marine and anadromous fishes in the North Atlantic and North Pacific Oceans. Among populations of Pacific herring (Clupea pallasii) on the west coast of North America the disease causes anemia and elevated mortality in periodic epizootics. Presently, VEN is diagnosed by observation of typical
Authors
Eveline J. Emmenegger, Jolene A. Glenn, James R. Winton, William N. Batts, Jacob L. Gregg, Paul K. Hershberger
Isolation and molecular characterization of a novel picornavirus from baitfish in the USA
During both regulatory and routine surveillance sampling of baitfish from the states of Illinois, Minnesota, Montana, and Wisconsin, USA, isolates (n = 20) of a previously unknown picornavirus were obtained from kidney/spleen or entire viscera of fathead minnows (Pimephales promelas) and brassy minnows (Hybognathus hankinsoni). Following the appearance of a diffuse cytopathic effect, examination o
Authors
Nicholas B.D. Phelps, Sunil K. Mor, Anibal G. Armien, William N. Batts, Andrew E. Goodwin, Lacey Hopper, Rebekah McCann, Terry Fei Fan Ng, Corey Puzach, Thomas B. Waltzek, Eric Delwart, James Winton, Sagar M. Goyal
Universal reverse-transcriptase real-time PCR for infectious hematopoietic necrosis virus (IHNV)
Infectious hematopoietic necrosis virus (IHNV) is an acute pathogen of salmonid fishes in North America, Europe and Asia and is reportable to the World Organization for Animal Health (OIE). Phylogenetic analysis has identified 5 major virus genogroups of IHNV worldwide, designated U, M, L, E and J; multiple subtypes also exist within those genogroups. Here, we report the development and validation
Authors
Maureen K. Purcell, Rachel L. Thompson, Kyle A. Garver, Laura M. Hawley, William N. Batts, Laura Sprague, Corie Sampson, James R. Winton
Viral hemorrhagic septicemia
Viral hemorrhagic septicemia (VHS) is one of the most important viral diseases of finfish worldwide. In the past, VHS was thought to affect mainly rainbow trout Oncorhynchus mykiss reared at freshwater facilities in Western Europe where it was known by various names including Egtved disease and infectious kidney swelling and liver degeneration (Wolf 1988). Today, VHS is known as an important sourc
Authors
William N. Batts, James R. Winton
Genetic analysis of a novel nidovirus from fathead minnows
A bacilliform virus was isolated from diseased fathead minnows (Pimephales promelas). Analysis of the complete genome coding for the polyprotein (pp1ab), spike (S), membrane (M) and nucleocapsid (N) proteins revealed that the virus was most like white bream virus (WBV), another bacilliform virus isolated from white bream (Blicca bjoerkna L.) and the type species of the genus Bafinivirus within the
Authors
William N. Batts, Andrew E. Goodwin, James R. Winton
A novel member of the family Hepeviridae from cutthroat trout (Oncorhynchus clarkii)
Beginning in 1988, the Chinook salmon embryo (CHSE-214) cell line was used to isolate a novel virus from spawning adult trout in the state of California, USA. Termed the cutthroat trout (Oncorhynchus clarkii) virus (CTV), the small, round virus was not associated with disease, but was subsequently found to be present in an increasing number of trout populations in the western USA, likely by a comb
Authors
William Batts, Susan Yun, Ronald Hedrick, James Winton
Emergence of viral hemorrhagic septicemia virus in the North American Great Lakes region is associated with low viral genetic diversity
Viral hemorrhagic septicemia virus (VHSV) is a fish rhabdovirus that causes disease in a broad range of marine and freshwater hosts. The known geographic range includes the Northern Atlantic and Pacific Oceans, and recently it has invaded the Great Lakes region of North America. The goal of this work was to characterize genetic diversity of Great Lakes VHSV isolates at the early stage of this vir
Authors
T.M. Thompson, W.N. Batts, M. Faisal, P. Bowser, J.W. Casey, K. Phillips, K.A. Garver, J. Winton, Gael Kurath
Detection of Viral Hemorrhagic Septicemia Virus by Quantitative Reverse Transcription Polymerase Chain Reaction from Two Fish Species at Two Sites in Lake Superior
Viral hemorrhagic septicemia virus (VHSV) was first detected in the Laurentian Great Lakes in 2005 during a mortality event in the Bay of Quinte, Lake Ontario. Subsequent analysis of archived samples determined that the first known isolation of VHSV in the Laurentian Great Lakes was from a muskellunge Esox masquinongy collected in Lake St. Clair in 2003. By the end of 2008, mortality events and vi
Authors
Emily R. Cornwell, Geofrey E. Eckerlin, Rodman G. Getchell, Geoffrey H. Groocock, Tarin M. Thompson, William N. Batts, Rufina N. Casey, Gael Kurath, James R. Winton, Paul R. Bowser, Mark B. Bain, James W. Casey
Establishment and partial characterization of a cell line from burbot Lota lota maculosa: susceptibility to IHNV, IPNV and VHSV.
This study describes the development and partial characterization of a continuous fibroblastic-like cell line (BEF-1) developed from late stage embryos of North American burbot Lota lota maculosa. This cell line has been maintained for over 5 yr and 100 passages in vitro. Cells were cultured using Eagle’s minimum essential medium with Earle’s salts (MEM) supplemented with GlutaMAX™, and 10% fetal
Authors
William N. Batts, Mark P. Polinski, John D. Drennan, Susan C. Ireland, Kenneth D. Cain
Current lineages of the epithelioma papulosum cyprini (EPC) cell line are contaminated with fathead minnow, Pimephales promelas, cells
Initially established from proliferative skin lesions of the common carp, Cyprinus carpio L., the epithelioma papulosum cyprini (EPC) cell line (Fijan, Sulimanovic, Bearzotti, Muzinic, Zwillenberg, Chilmonczyk, Vautherot & de Kinkelin 1983) has become one of the most widely used tools for research on fish viruses and the diagnosis of fish viral diseases.
Authors
J. Winton, W. Batts, P. DeKinkelin, M. LeBerre, M. Bremont, N. Fijan
Distribution of an invasive aquatic pathogen (viral hemorrhagic septicemia virus) in the Great Lakes and its relationship to shipping
Viral hemorrhagic septicemia virus (VHSV) is a rhabdovirus found in fish from oceans of the northern hemisphere and freshwaters of Europe. It has caused extensive losses of cultured and wild fish and has become established in the North American Great Lakes. Large die-offs of wild fish in the Great Lakes due to VHSV have alarmed the public and provoked government attention on the introduction and s
Authors
Mark B. Bain, Emily R. Cornwell, Kristine M. Hope, Geofrey E. Eckerlin, Rufina N. Casey, Geoffrey H. Groocock, Rodman G. Getchell, Paul R. Bowser, James R. Winton, William N. Batts, Allegra Cangelosi, James W. Casey
Transcriptome analysis of rainbow trout infected with high and low virulence strains of Infectious hematopoietic necrosis virus
There are three main genetic lineages or genogroups of Infectious hematopoietic necrosis virus (IHNV) in N. America. Strains representing the M genogroup are more virulent in rainbow trout relative to the U genogroup. In this study, we used microarray analysis to evaluate potential mechanisms responsible for host-specific virulence in rainbow trout that were given intraperitoneal injections of buf
Authors
Maureen K. Purcell, Inderjit Singh Marjara, William Batts, Gael Kurath, John D. Hansen
Science and Products
- Publications
Filter Total Items: 57
Molecular identification of erythrocytic necrosis virus (ENV) from the blood of Pacific herring (Clupea pallasii)
Viral erythrocytic necrosis (VEN) is a condition affecting the red blood cells of more than 20 species of marine and anadromous fishes in the North Atlantic and North Pacific Oceans. Among populations of Pacific herring (Clupea pallasii) on the west coast of North America the disease causes anemia and elevated mortality in periodic epizootics. Presently, VEN is diagnosed by observation of typicalAuthorsEveline J. Emmenegger, Jolene A. Glenn, James R. Winton, William N. Batts, Jacob L. Gregg, Paul K. HershbergerIsolation and molecular characterization of a novel picornavirus from baitfish in the USA
During both regulatory and routine surveillance sampling of baitfish from the states of Illinois, Minnesota, Montana, and Wisconsin, USA, isolates (n = 20) of a previously unknown picornavirus were obtained from kidney/spleen or entire viscera of fathead minnows (Pimephales promelas) and brassy minnows (Hybognathus hankinsoni). Following the appearance of a diffuse cytopathic effect, examination oAuthorsNicholas B.D. Phelps, Sunil K. Mor, Anibal G. Armien, William N. Batts, Andrew E. Goodwin, Lacey Hopper, Rebekah McCann, Terry Fei Fan Ng, Corey Puzach, Thomas B. Waltzek, Eric Delwart, James Winton, Sagar M. GoyalUniversal reverse-transcriptase real-time PCR for infectious hematopoietic necrosis virus (IHNV)
Infectious hematopoietic necrosis virus (IHNV) is an acute pathogen of salmonid fishes in North America, Europe and Asia and is reportable to the World Organization for Animal Health (OIE). Phylogenetic analysis has identified 5 major virus genogroups of IHNV worldwide, designated U, M, L, E and J; multiple subtypes also exist within those genogroups. Here, we report the development and validationAuthorsMaureen K. Purcell, Rachel L. Thompson, Kyle A. Garver, Laura M. Hawley, William N. Batts, Laura Sprague, Corie Sampson, James R. WintonViral hemorrhagic septicemia
Viral hemorrhagic septicemia (VHS) is one of the most important viral diseases of finfish worldwide. In the past, VHS was thought to affect mainly rainbow trout Oncorhynchus mykiss reared at freshwater facilities in Western Europe where it was known by various names including Egtved disease and infectious kidney swelling and liver degeneration (Wolf 1988). Today, VHS is known as an important sourcAuthorsWilliam N. Batts, James R. WintonGenetic analysis of a novel nidovirus from fathead minnows
A bacilliform virus was isolated from diseased fathead minnows (Pimephales promelas). Analysis of the complete genome coding for the polyprotein (pp1ab), spike (S), membrane (M) and nucleocapsid (N) proteins revealed that the virus was most like white bream virus (WBV), another bacilliform virus isolated from white bream (Blicca bjoerkna L.) and the type species of the genus Bafinivirus within theAuthorsWilliam N. Batts, Andrew E. Goodwin, James R. WintonA novel member of the family Hepeviridae from cutthroat trout (Oncorhynchus clarkii)
Beginning in 1988, the Chinook salmon embryo (CHSE-214) cell line was used to isolate a novel virus from spawning adult trout in the state of California, USA. Termed the cutthroat trout (Oncorhynchus clarkii) virus (CTV), the small, round virus was not associated with disease, but was subsequently found to be present in an increasing number of trout populations in the western USA, likely by a combAuthorsWilliam Batts, Susan Yun, Ronald Hedrick, James WintonEmergence of viral hemorrhagic septicemia virus in the North American Great Lakes region is associated with low viral genetic diversity
Viral hemorrhagic septicemia virus (VHSV) is a fish rhabdovirus that causes disease in a broad range of marine and freshwater hosts. The known geographic range includes the Northern Atlantic and Pacific Oceans, and recently it has invaded the Great Lakes region of North America. The goal of this work was to characterize genetic diversity of Great Lakes VHSV isolates at the early stage of this virAuthorsT.M. Thompson, W.N. Batts, M. Faisal, P. Bowser, J.W. Casey, K. Phillips, K.A. Garver, J. Winton, Gael KurathDetection of Viral Hemorrhagic Septicemia Virus by Quantitative Reverse Transcription Polymerase Chain Reaction from Two Fish Species at Two Sites in Lake Superior
Viral hemorrhagic septicemia virus (VHSV) was first detected in the Laurentian Great Lakes in 2005 during a mortality event in the Bay of Quinte, Lake Ontario. Subsequent analysis of archived samples determined that the first known isolation of VHSV in the Laurentian Great Lakes was from a muskellunge Esox masquinongy collected in Lake St. Clair in 2003. By the end of 2008, mortality events and viAuthorsEmily R. Cornwell, Geofrey E. Eckerlin, Rodman G. Getchell, Geoffrey H. Groocock, Tarin M. Thompson, William N. Batts, Rufina N. Casey, Gael Kurath, James R. Winton, Paul R. Bowser, Mark B. Bain, James W. CaseyEstablishment and partial characterization of a cell line from burbot Lota lota maculosa: susceptibility to IHNV, IPNV and VHSV.
This study describes the development and partial characterization of a continuous fibroblastic-like cell line (BEF-1) developed from late stage embryos of North American burbot Lota lota maculosa. This cell line has been maintained for over 5 yr and 100 passages in vitro. Cells were cultured using Eagle’s minimum essential medium with Earle’s salts (MEM) supplemented with GlutaMAX™, and 10% fetalAuthorsWilliam N. Batts, Mark P. Polinski, John D. Drennan, Susan C. Ireland, Kenneth D. CainCurrent lineages of the epithelioma papulosum cyprini (EPC) cell line are contaminated with fathead minnow, Pimephales promelas, cells
Initially established from proliferative skin lesions of the common carp, Cyprinus carpio L., the epithelioma papulosum cyprini (EPC) cell line (Fijan, Sulimanovic, Bearzotti, Muzinic, Zwillenberg, Chilmonczyk, Vautherot & de Kinkelin 1983) has become one of the most widely used tools for research on fish viruses and the diagnosis of fish viral diseases.AuthorsJ. Winton, W. Batts, P. DeKinkelin, M. LeBerre, M. Bremont, N. FijanDistribution of an invasive aquatic pathogen (viral hemorrhagic septicemia virus) in the Great Lakes and its relationship to shipping
Viral hemorrhagic septicemia virus (VHSV) is a rhabdovirus found in fish from oceans of the northern hemisphere and freshwaters of Europe. It has caused extensive losses of cultured and wild fish and has become established in the North American Great Lakes. Large die-offs of wild fish in the Great Lakes due to VHSV have alarmed the public and provoked government attention on the introduction and sAuthorsMark B. Bain, Emily R. Cornwell, Kristine M. Hope, Geofrey E. Eckerlin, Rufina N. Casey, Geoffrey H. Groocock, Rodman G. Getchell, Paul R. Bowser, James R. Winton, William N. Batts, Allegra Cangelosi, James W. CaseyTranscriptome analysis of rainbow trout infected with high and low virulence strains of Infectious hematopoietic necrosis virus
There are three main genetic lineages or genogroups of Infectious hematopoietic necrosis virus (IHNV) in N. America. Strains representing the M genogroup are more virulent in rainbow trout relative to the U genogroup. In this study, we used microarray analysis to evaluate potential mechanisms responsible for host-specific virulence in rainbow trout that were given intraperitoneal injections of bufAuthorsMaureen K. Purcell, Inderjit Singh Marjara, William Batts, Gael Kurath, John D. Hansen - Science
- Data
No Result Found