This dataset includes PRISM climate data from the AN81m model, extracted to the USGS 12-Digit Hydrologic Unit (HUC-12 basins) spatial grain. Yearly data is available for 83,304 HUC-12 basins from 1895-2017, and variables include annual precipitation, annual means of maximum and minimum daily average air temperature, maximum daily air temperature in August, minimum daily air temperature in January, daily mean dewpoint temperature, and minimum and maximum daily vapor pressure deficits.