We synthesized existing literature to develop this dataset which relates suspended sediment concentration and exposure duration to biological effects on fishes. Our dataset contains a total of 3,610 dose-response data triplicates consisting of (a) suspended sediment concentration, (b) duration of exposure, and (c) fish severity of ill effects (SEV). There is no original data in the dataset. Please contact Annika Walters for a full list of references or any questions regarding the attached data.