CWDPRNP: A tool for cervid prion sequence analysis in program R
October 1, 2017
Chronic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which affects economically and ecologically important members of the family Cervidae. Single nucleotide polymorphisms within the prion protein gene have been linked to differential susceptibility to the disease in many species. Wildlife managers are seeking to determine the frequencies of disease-associated alleles and genotypes and delineate spatial genetic patterns. The CWDPRNP package, implemented in program R, provides a unified framework for analyzing prion protein gene variability and spatial structure.
Citation Information
Publication Year | 2017 |
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Title | CWDPRNP: A tool for cervid prion sequence analysis in program R |
DOI | 10.1093/bioinformatics/btx333 |
Authors | William L. Miller, W. David Walter |
Publication Type | Article |
Publication Subtype | Journal Article |
Series Title | Bioinformatics |
Index ID | 70193542 |
Record Source | USGS Publications Warehouse |
USGS Organization | Coop Res Unit Leetown |