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CWDPRNP: A tool for cervid prion sequence analysis in program R

October 1, 2017

Chronic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which affects economically and ecologically important members of the family Cervidae. Single nucleotide polymorphisms within the prion protein gene have been linked to differential susceptibility to the disease in many species. Wildlife managers are seeking to determine the frequencies of disease-associated alleles and genotypes and delineate spatial genetic patterns. The CWDPRNP package, implemented in program R, provides a unified framework for analyzing prion protein gene variability and spatial structure.

Citation Information

Publication Year 2017
Title CWDPRNP: A tool for cervid prion sequence analysis in program R
DOI 10.1093/bioinformatics/btx333
Authors William L. Miller, W. David Walter
Publication Type Article
Publication Subtype Journal Article
Series Title Bioinformatics
Index ID 70193542
Record Source USGS Publications Warehouse
USGS Organization Coop Res Unit Leetown