DDE: Interference with extra-renal salt excretion in the mallard

The effects of DDE on the function of the salt gland, the main route of sodium chloride excretion in marine birds, were investigated in mature mallards, Anas platyrhynchos, maintained on either fresh water or 1 percent salt water and given 0, 10, 100, or 1000 ppm DDE in the diet (12 birds per level). The rate of sodium chloride excretion by the salt gland following injections of concentrated salt solutions was not reduced (from that of controls) in DDE-treated birds maintained on salt water, but was significantly reduced in DDE-treated birds not previously given salt.