Water-quality data for wells and springs in the Powder River basin in northeastern Wyoming are presented in three tables. The first table lists results of analyses of common constituents for 748 ground-water sites. The second table presents dissolved-trace-metal data for 220 ground-water sites. Radiochemical data are listed in the third table for 65 ground-water sites. The locations of the sites listed in the tables are shown on a map of the area.