A detailed study of the hydrographic features of the Susquehanna River drainage basin has revealed the existence of a large amount of interesting data. These, however, are widely distributed in various publications and manuscripts which are in most cases inaccessible. This paper has been prepared to meet the constant demand for this information from both the general and the engineering public. The general deductions are intended to give the general reader a comprehensive review of the principal conditions which exist in this area, while the base data have been given for the use of the engineer, so that he may make his own deductions and have sufficient data for estimates in hydraulic investigations.