In this study, largemouth bass (LMB) were subchronically exposed to p,p′-DDE or dieldrin in their diet to evaluate the effect of exposure on expression of genes involved in reproduction and steroid homeostasis. Using real-time PCR, we detected a different gene expression pattern for each OCP, suggesting that they each affect LMB in a different way. We also detected a different expression pattern among sexes, suggesting that sexes are affected differently by OCPs perhaps reflecting the different adaptive responses of each sex to dysregulation caused by OCP exposure.
|Title||Modeling of gene expression pattern alteration by p,p′-DDE and dieldrin in largemouth bass|
|Authors||Natalia Garcia-Reyero, David Barber, Timothy Gross, Nancy Denslow|
|Publication Subtype||Journal Article|
|Series Title||Marine Environmental Research|
|Record Source||USGS Publications Warehouse|