Conventional reservoir quality data for more than 300 wells provided by the Illinois and Indiana State Geological Surveys were analyzed to determine the factors governing porosity and permeability in the Upper Mississippian Bethel Sandstone and Cypress Sandstone, two of the principal producing units in the Illinois Basin. In addition, approximately 150 samples of the Bethel Sandstone-Cypress Sandstone interval from about 80 wells in the Illinois Basin were collected for mineralogical and geochemical analysis to reconstruct the burial and diagenetic history and to establish the timing of diagenesis relative to the entrapment of hydrocarbons. One aspect of the study involved linking inorganic and organic diagenesis to late Paleozoic tectonism and hydrothermal fluid-flow events in the region.