Residue dynamics of quinaldine and TFM in rainbow trout

Study of the residue dynamics of 2-methylquinoline (quinaldine) and 3-trifluoromethyl-4-nitrophenol (TFM) in rainbow trout yielded the following findings:

1. Uptake and distribution of TFM by trout was influenced by the biotransformation of the lipidsoluble free phenol. No such effect was observed with quinaldine.

2. Disappearance of quinaldine and TFM from gallbladder bile was slower than from plasma or muscle during 24 hr of withdrawal in fresh water.

3. The concentration of TFM conjugate may exceed that of free TFM in bile by a factor of 10³.