This report presents procedures for estimating low-flow frequency characteristics for streams in the Susquehanna River basin. The techniques can be used at ungaged sites as well as sites where insufficient data are available to make a reliable estimate. Streams have been divided intp two types--major and minor. Major streams are the Susquehanna, West Branch Susquehanna, Juniata, and Chemung Rivers. Points on these streams with drainage areas of more than 2,000 mi 2 (5,180 km 2 ) are included in this category. Points on these streams with drainage areas of less than 2,000 mi 2 fall into the minor stream category. Generally minor streams are herein defined as those draining less than 2,000 mi 2 (5,180 km 2 ). Multiple -regression techniques have been used to develop relations for estimating the 1-, 3-, 7-, 30-, and 183-day duration low flows at recurrence intervals of 10, 20, SO and 100 years for annual series data and the 1 - , 3-, 7-, and 30-day duration low flows, at the same recurrence intervals, for six individual months, May through October, inclusive.