Skip to main content
U.S. flag

An official website of the United States government

Gene-expression signatures of Atlantic salmon's plastic life cycle

January 1, 2009

How genomic expression differs as a function of life history variation is largely unknown. Atlantic salmon exhibits extreme alternative life histories. We defined the gene-expression signatures of wild-caught salmon at two different life stages by comparing the brain expression profiles of mature sneaker males and immature males, and early migrants and late migrants. In addition to life-stage-specific signatures, we discovered a surprisingly large gene set that was differentially regulated-at similar magnitudes, yet in opposite direction-in both life history transitions. We suggest that this co-variation is not a consequence of many independent cellular and molecular switches in the same direction but rather represents the molecular equivalent of a physiological shift orchestrated by one or very few master regulators. ?? 2009 Elsevier Inc. All rights reserved.

Publication Year 2009
Title Gene-expression signatures of Atlantic salmon's plastic life cycle
DOI 10.1016/j.ygcen.2009.04.021
Authors N. Aubin-Horth, B. H. Letcher, H.A. Hofmann
Publication Type Article
Publication Subtype Journal Article
Series Title General and Comparative Endocrinology
Index ID 70036647
Record Source USGS Publications Warehouse