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Intra-strain dioxin sensitivity and morphometric effects in swim-up rainbow trout (Oncorhynchus mykiss)

January 1, 2004

Inter and intra-specific differences in sensitivity of early life stage salmonids to 2,3,7,8-TCDD exposure have been reported, but intra-strain differences have not been found in the literature. Our results indicate that intra-strain variability in terms of embryo mortality (LD50) is small in Eagle Lake strain of rainbow trout, LD50 values ranging from 285 to 457 pg TCDD egg g−1. These results confirm Eagle Lake as a less sensitive strain within rainbow trout, and do not indicate overlap with reported LD50 values for brook or lake trout. Our results also demonstrate that although generalized edema in regions including the yolk-sac are frequently associated with mortality following dioxin exposure, not all edematous fish die. We detected dose-dependent decreases in cranial length, eye diameter, mass, and total length (P

Publication Year 2004
Title Intra-strain dioxin sensitivity and morphometric effects in swim-up rainbow trout (Oncorhynchus mykiss)
DOI 10.1016/j.cca.2003.12.005
Authors Paulo S. M. Carvalho, Douglas B. Noltie, D. E. Tillitt
Publication Type Article
Publication Subtype Journal Article
Series Title Comparative Biochemistry and Physiology, Part C: Toxicology & Pharmacology
Index ID 70027066
Record Source USGS Publications Warehouse
USGS Organization Columbia Environmental Research Center
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