The probabilistic methodology developed by the U.S. Geological Survey is applied to a new seismic hazard assessment for Puerto Rico and the U.S. Virgin Islands. Modeled seismic sources include gridded historical seismicity, subduction-interface and strike-slip faults with known slip rates, and two broad zones of crustal extension with seismicity rates constrained by GPS geodesy. We use attenuation relations from western North American and worldwide data, as well as a Caribbean-specific relation. Results are presented as maps of peak ground acceleration and 0.2- and 1.0-second spectral response acceleration for 2% and 10% probabilities of exceedance in 50 years (return periods of about 2,500 and 500 years, respectively). This paper describes the hazard model and maps that were balloted by the Building Seismic Safety Council and recommended for the 2003 NEHRP Provisions and the 2006 International Building Code. ?? 2010, Earthquake Engineering Research Institute.