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Vaccination against bacterial kidney disease

March 7, 2014

Bacterial kidney disease (BKD) of salmonid fishes, caused by Renibacterium salmoninarum, has been recognized as a serious disease in salmonid fishes since the 1930s. This chapter discusses the occurrence and significance, etiology, and pathogenesis of BKD. It then describes the different vaccination procedures and the effects and side-effects of vaccination. Despite years of research, however, only a single vaccine has been licensed for prevention of BKD, and has demonstrated variable efficacy. Therefore, in addition to a presentation of the current status of BKD vaccination, a discussion of potential future directions for BKD vaccine development is included in the chapter. This discussion is focused on the unique characteristics of R. salmoninarum and its biology, as well as aspects of the salmonid immune system that might be explored specifically to develop more effective vaccines for BKD prevention.

Publication Year 2014
Title Vaccination against bacterial kidney disease
DOI 10.1002/9781118806913.ch22
Authors Diane G. Elliott, Gregory D. Wiens, K. Larry Hammell, Linda D. Rhodes
Publication Type Book Chapter
Publication Subtype Book Chapter
Index ID 70101338
Record Source USGS Publications Warehouse
USGS Organization Western Fisheries Research Center