Erik Hofmeister
Erik Hofmeister is a Research Virologist at the National Wildlife Health Center.
Science and Products
LAMP assay for detection of Asian fish tapeworm LAMP assay for detection of Asian fish tapeworm
Data are relative fluorescent units obtained from the FAM channel of a AmpliFire Isothermal Fluorometer (Agdia, Inc., Elkhart, USA) recorded every 10 sec during as isothermal (LAMP) amplification. The isothermal reaction is to detect the Asian fish tapeworm, Schyzocotyle acheilognathi [syn. Bothriocephalus]. Samples (column headers) are described in tabs and include 1) positive control...
Dataset: Acute oral toxicity and tissue residues of saxitoxin in the mallard (Anas platyrhynchos) Dataset: Acute oral toxicity and tissue residues of saxitoxin in the mallard (Anas platyrhynchos)
This data set is composed of data collected from an experimental study inoculating mallard ducks (Anas platyrhynchos) with Saxitoxin and associated control ducks. Data includes the specific of inoculation, observational behavioral data, daily weights, dosing, results of inoculation, testing of samples collected throughout the study, and necropsy results.
West Nile virus susceptibility of American singer canaries: Data West Nile virus susceptibility of American singer canaries: Data
hree datasets are included: 1) survival of domesticated canaries and American crows following sub-cutaneous challenges ranging from 101 105 plaque forming units of West Nile virus. 2) Arbitrary units of WNV detected by RT-PCR or plaque forming units of WNV cultured in vero cells in 4 separate studies. Culture results are indicated for each day post WNV challenge. 3) Weight (mass)...
An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus
Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control...
Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata), a songbird model for immune function: Data Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata), a songbird model for immune function: Data
The data set contains paired-end, 100 nucleotide long RNA sequencing reads for each sample. Raw sequencing reads ranged from 18-30million reads per sample. Quality trimmed reads were mapped to the Zebra Finch reference genome with an average of 79.0-80.8% mapping rate, corresponding to 18,618 Ensembl gene IDs. Of these, 14,114 genes averaged at least 5 mapped reads across all samples and...
Susceptibility and antibody response of the laboratory model zebra finch Susceptibility and antibody response of the laboratory model zebra finch
The data set contains the results of experimental challenge of captive zebra finches with an American crow isolate of West Nile virus. Data include infectivity, mortality, viremia, oral shedding of virus, and serology for anti- WNV antibodies. Australian and Timor zebra finches were used in this study and both are useful as a laboratory model of an avian species with moderate...
Filter Total Items: 36
Population differences in susceptibility to Plasmodium relictum in zebra finches Taeniopygia guttata Population differences in susceptibility to Plasmodium relictum in zebra finches Taeniopygia guttata
Domesticated Australian and Timor zebra finches (Taeniopygia guttata castanotis, and T. guttata guttata, respectively) were inoculated with canary (Serinus canaria) blood containing a Hawaiian isolate of Plasmodium relictum (lineage GRW04), a hemoparasite that causes avian malaria. In two experimental trials, Timor, but not Australian zebra finches developed parasitemia that was detected...
Authors
Erik K. Hofmeister, Christopher N. Balakrishnan, Carter T. Atkinson
Effect of climate change on disease spread in wildlife Effect of climate change on disease spread in wildlife
A growing body of evidence indicates that climate change alone, or acting synergistically with current anthropogenic threats, is affecting the health of wild populations of aquatic and terrestrial wildlife. Measurable by-products of climate change include elevated atmospheric concentrations of greenhouse gases, higher average global temperatures; variations in global precipitation...
Authors
Erik K. Hofmeister, Caroline R. Van Hemert
West Nile virus infection in American singer canaries: An experimental model in a highly susceptible avian species West Nile virus infection in American singer canaries: An experimental model in a highly susceptible avian species
This study investigated the susceptibility of American singer canaries (Serinus canaria) to West Nile virus (WNV) infection. Adult canaries were inoculated with 105, 102, and 101plaque forming units (PFU) of WNV. All birds became infected and mortality occurred by 5 days postinoculation. The load of viral RNA as determined by RT-qPCR was dose dependent, and was higher at all doses than...
Authors
Erik K. Hofmeister, Melissa Lund, Valerie I. Shearn-Bochsler
An examination of the effect of aerosolized permanone insecticide on zebra finch susceptibility to West Nile virus An examination of the effect of aerosolized permanone insecticide on zebra finch susceptibility to West Nile virus
West Nile virus is primarily maintained cryptically primarily in avian (Passerine) populations where it is transmitted by Culex spp. mosquitoes. Mosquito control measures currently include physical activities to reduce mosquito breeding sites, the application of mosquito larvicides, or aerosolized insecticides to kill adults (adulticides) when arboviral diseases such as West Nile virus...
Authors
Mark D. Jankowski, E. Moore Murray, Erik K. Hofmeister
Stress hormones predict a host superspreader phenotype in the West Nile virus system Stress hormones predict a host superspreader phenotype in the West Nile virus system
Glucocorticoid stress hormones, such as corticosterone (CORT), have profound effects on the behaviour and physiology of organisms, and thus have the potential to alter host competence and the contributions of individuals to population- and community-level pathogen dynamics. For example, CORT could alter the rate of contacts among hosts, pathogens and vectors through its widespread...
Authors
Stephanie Gervasi, Sarah Burgan, Erik K. Hofmeister, Thomas R. Unnasch, Lynn B. Martin
Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata) Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata)
West Nile virus (WNV) is a widespread arbovirus that imposes a significant cost to both human and wildlife health. WNV exists in a bird-mosquito transmission cycle in which passerine birds act as the primary reservoir host. As a public health concern, the mammalian immune response to WNV has been studied in detail. Little, however, is known about the avian immune response to WNV. Avian...
Authors
Daniel J. Newhouse, Erik K. Hofmeister, Christopher N. Balakrishnan
Science and Products
LAMP assay for detection of Asian fish tapeworm LAMP assay for detection of Asian fish tapeworm
Data are relative fluorescent units obtained from the FAM channel of a AmpliFire Isothermal Fluorometer (Agdia, Inc., Elkhart, USA) recorded every 10 sec during as isothermal (LAMP) amplification. The isothermal reaction is to detect the Asian fish tapeworm, Schyzocotyle acheilognathi [syn. Bothriocephalus]. Samples (column headers) are described in tabs and include 1) positive control...
Dataset: Acute oral toxicity and tissue residues of saxitoxin in the mallard (Anas platyrhynchos) Dataset: Acute oral toxicity and tissue residues of saxitoxin in the mallard (Anas platyrhynchos)
This data set is composed of data collected from an experimental study inoculating mallard ducks (Anas platyrhynchos) with Saxitoxin and associated control ducks. Data includes the specific of inoculation, observational behavioral data, daily weights, dosing, results of inoculation, testing of samples collected throughout the study, and necropsy results.
West Nile virus susceptibility of American singer canaries: Data West Nile virus susceptibility of American singer canaries: Data
hree datasets are included: 1) survival of domesticated canaries and American crows following sub-cutaneous challenges ranging from 101 105 plaque forming units of West Nile virus. 2) Arbitrary units of WNV detected by RT-PCR or plaque forming units of WNV cultured in vero cells in 4 separate studies. Culture results are indicated for each day post WNV challenge. 3) Weight (mass)...
An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus
Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control...
Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata), a songbird model for immune function: Data Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata), a songbird model for immune function: Data
The data set contains paired-end, 100 nucleotide long RNA sequencing reads for each sample. Raw sequencing reads ranged from 18-30million reads per sample. Quality trimmed reads were mapped to the Zebra Finch reference genome with an average of 79.0-80.8% mapping rate, corresponding to 18,618 Ensembl gene IDs. Of these, 14,114 genes averaged at least 5 mapped reads across all samples and...
Susceptibility and antibody response of the laboratory model zebra finch Susceptibility and antibody response of the laboratory model zebra finch
The data set contains the results of experimental challenge of captive zebra finches with an American crow isolate of West Nile virus. Data include infectivity, mortality, viremia, oral shedding of virus, and serology for anti- WNV antibodies. Australian and Timor zebra finches were used in this study and both are useful as a laboratory model of an avian species with moderate...
Filter Total Items: 36
Population differences in susceptibility to Plasmodium relictum in zebra finches Taeniopygia guttata Population differences in susceptibility to Plasmodium relictum in zebra finches Taeniopygia guttata
Domesticated Australian and Timor zebra finches (Taeniopygia guttata castanotis, and T. guttata guttata, respectively) were inoculated with canary (Serinus canaria) blood containing a Hawaiian isolate of Plasmodium relictum (lineage GRW04), a hemoparasite that causes avian malaria. In two experimental trials, Timor, but not Australian zebra finches developed parasitemia that was detected...
Authors
Erik K. Hofmeister, Christopher N. Balakrishnan, Carter T. Atkinson
Effect of climate change on disease spread in wildlife Effect of climate change on disease spread in wildlife
A growing body of evidence indicates that climate change alone, or acting synergistically with current anthropogenic threats, is affecting the health of wild populations of aquatic and terrestrial wildlife. Measurable by-products of climate change include elevated atmospheric concentrations of greenhouse gases, higher average global temperatures; variations in global precipitation...
Authors
Erik K. Hofmeister, Caroline R. Van Hemert
West Nile virus infection in American singer canaries: An experimental model in a highly susceptible avian species West Nile virus infection in American singer canaries: An experimental model in a highly susceptible avian species
This study investigated the susceptibility of American singer canaries (Serinus canaria) to West Nile virus (WNV) infection. Adult canaries were inoculated with 105, 102, and 101plaque forming units (PFU) of WNV. All birds became infected and mortality occurred by 5 days postinoculation. The load of viral RNA as determined by RT-qPCR was dose dependent, and was higher at all doses than...
Authors
Erik K. Hofmeister, Melissa Lund, Valerie I. Shearn-Bochsler
An examination of the effect of aerosolized permanone insecticide on zebra finch susceptibility to West Nile virus An examination of the effect of aerosolized permanone insecticide on zebra finch susceptibility to West Nile virus
West Nile virus is primarily maintained cryptically primarily in avian (Passerine) populations where it is transmitted by Culex spp. mosquitoes. Mosquito control measures currently include physical activities to reduce mosquito breeding sites, the application of mosquito larvicides, or aerosolized insecticides to kill adults (adulticides) when arboviral diseases such as West Nile virus...
Authors
Mark D. Jankowski, E. Moore Murray, Erik K. Hofmeister
Stress hormones predict a host superspreader phenotype in the West Nile virus system Stress hormones predict a host superspreader phenotype in the West Nile virus system
Glucocorticoid stress hormones, such as corticosterone (CORT), have profound effects on the behaviour and physiology of organisms, and thus have the potential to alter host competence and the contributions of individuals to population- and community-level pathogen dynamics. For example, CORT could alter the rate of contacts among hosts, pathogens and vectors through its widespread...
Authors
Stephanie Gervasi, Sarah Burgan, Erik K. Hofmeister, Thomas R. Unnasch, Lynn B. Martin
Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata) Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata)
West Nile virus (WNV) is a widespread arbovirus that imposes a significant cost to both human and wildlife health. WNV exists in a bird-mosquito transmission cycle in which passerine birds act as the primary reservoir host. As a public health concern, the mammalian immune response to WNV has been studied in detail. Little, however, is known about the avian immune response to WNV. Avian...
Authors
Daniel J. Newhouse, Erik K. Hofmeister, Christopher N. Balakrishnan