The U.S. Geological Survey South Atlantic Water Science Center, in cooperation with the South Carolina Department of Transportation, implemented a South Carolina StreamStats application in 2018. This shapefile dataset contains vector lines representing streams, rivers, and ditches that were used in preparing the underlying data for the South Carolina StreamStats application. Data were compiled from multiple sources, but principally represent lidar-derived linework from the South Carolina Department of Natural Resources and the South Carolina Lidar Consortium.The South Carolina hydrography lines were created from elevation rasters that ranged from 4 to 10 ft resolution, to produce a product of approximately 1:6,000-scale. Other sources include the 1:24,000 scale high resolution National Hydrography Dataset streamlines [for streamlines in Georgetown County (SC), NC, and GA] and the 1:4,800 scale local-resolution North Carolina Stream Mapping Project lines (mountain counties). These vector lines were used to enforce drainages on digital elevation model raster grids using the HydroDem/Agree program during data preparation.