The Andes Mountains of South America host significant porphyry copper deposits. The region is the major global source of copper and an area of active mining, exploration, and development. The Andes region was included in USGS global compilations of porphyry deposits published by Singer and others in 2005 and 2008. Since that time, many new discoveries and new resource data have become available. This compilation includes new and updated location, references, and grade and tonnage data for porphyry copper deposits in the Andes along with grade and tonnage data from the previous compilations. The data release includes a data table, references, and shapefiles of porphyry copper locations and political boundaries.