Static Coulomb stress changes imparted by the February 21, 2008 Wells, Nevada earthquake are calculated, using an 8 x 6 km rectangular patch with a uniform slip as a source fault. Stress changes are resolved on nearby active faults using their rake, dip, and strike direction, assuming a fault friction of 0.4. The largest Coulomb stress increase (0.2 bars) imparted to surrounding major active faults from the Wells earthquake occurs on the Clover Hill fault, which may be the southern continuation of the ruptured fault. A 0.1 bar Coulomb stress increase is calculated on the western Snake Mountains fault. Coulomb stress decreases of 0.5 bars are calculated for the northern parts of the Independence and Ruby Mountains faults. The Coulomb stress change is calculated on relocated aftershocks assuming that they have the same strike, dip, and rake, as the source fault. Under this assumption, 75% of the aftershocks received a Coulomb stress increase.