The United States as a Nation possesses abundant water resources and has developed and used those resources extensively. The national renewable supply of water is about 1,400 billion gallons per day (for the conterminous 48 States). Approximately 380 billion gallons per day of freshwater is withdrawn for use by the Nation's homes, farms, and industries, and about 280 billion gallons per day is returned to streams. Although a large percentage of the Nation's waste is carried in this return flow, the quality of water in streams has improved in many respects as a result of the pollution-control pro- grams of recent years. However, much remains to be learned about water quality particularly the extent of contamination by synthetic organic chemicals and heavy metals, and the effects of these contaminants on human health.