The Poison Creek Anticline is a major fold that occupies a large part of the western part of the Lemhi Range. The fold is now broken by normal faults, but removal of displacement on the normal faults permitted reconstruction of the anticline. The fold formed during late Mesozoic compressional deformation in the hinterland of the Cordilleran thrust belt. It is in the hanging wall of the Poison Creek thrust fault, a major fault in east-central Idaho, that displaced Proterozoic strata over lower Paleozoic rocks.