This report summarizes the activities of the Southwest Florida Subdistrict of the U.S. Geological Survey, Water Resources Division for fiscal year 1977. The organization and mission of the subdistrict office are described. The cooperative program for fiscal year 1977 included 41 interpretive investigations. Abstracts of twenty reports released by the subdistrict during 1977 and an extensive bibliography of reports released from 1933 to 1977 are included. The hydrologic setting of southwest Florida is outlined followed by discussions of surface-water, ground-water, and quality-of-water conditions. Hydrologic conditions in southwest Florida in 1977 are shown by the presentation of hydrographs from selected surface-water, ground-water, and lake-stage data collection sites.