Donald Tillitt, PhD (Former Employee)
Science and Products
Filter Total Items: 215
Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure
This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish. A multitude of chemicals induce EROD activity in a variety of fish species, the most potent inducers being structural analogs of 2,3,7,8-tetracholordibenzo-p-dioxin...
Authors
J.J. Whyte, R.E. Jung, C. J. Schmitt, D. E. Tillitt
PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin
Adult walleye were collected from several locations in the Lower Fox River and Green Bay, Wisconsin (the assessment area) and two relatively uncontaminated reference locations (Lake Winnebago and Patten Lake, Wisconsin) between July and October in 1996 and 1997. Whole body and liver samples collected in 1996 were analyzed for total PCBs, PCB congeners, and liver histological lesions...
Authors
Mace G. Barron, Michael J. Anderson, Dave Cacela, Joshua Lipton, Swee J. Teh, David E. Hinton, Judith T. Zelikoff, Audrey L. Dikkeboom, Donald E. Tillitt, Mark Holey, Nancy Denslow
Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems
This document describes the suite of biological methods of the U.S. Geological Survey- Biomonitoring of Environmental Status and Trends program for monitoring chemical contaminants and their effects on fish. The methods, which were selected by panels of experts, are being field-tested in rivers of the Mississippi River, Columbia River, and Rio Grande basins. General health biomarkers...
Authors
Vicki S. Blazer, Nancy D. Denslow, Gail M. Dethloff, Timothy S. Gross, Kelly K. McDonald, Christopher J. Schmitt, Donald E. Tillitt, Jeffrey J. Whyte
Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts
The analysis of PCBs in fish tissues by immunoassay methods was evaluated using fish collected from a US monitoring program, the National Contaminant Biomonitoring Program of the US Department of Interior, Fish and Wildlife Service. Selected composite whole fish samples, which represented widely varying concentrations and sources of PCBs, were extracted and subjected to congener PCB...
Authors
J.L. Zajicek, D. E. Tillitt, T.R. Schwartz, C. J. Schmitt, R.O. Harrison
Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment
Polychlorinated naphthalenes (PCNs) are organic compounds with some chemical properties and uses similar to polychlorinated biphenyls. Polychlorinated naphthalenes have been detected in biota from certain aquatic environments. The toxicities of several PCN technical mixtures (Halowax) to medaka (Oryzias latipes) were determined by use of an embryo nanoinjection method. Medaka eggs (early...
Authors
Sergio A. Villalobos, Diana M. Papoulias, John C. Meadows, Alan L. Blankenship, Stephanie D. Pastva, Kurunthachalam Kannan, D.E. Hinton, Donald E. Tillitt, John P. Giesy
An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol
A model system was characterized which may be used as an in vivo screen for effects of chemicals or environmental mixtures on sexual differentiation and development of reproductive organs and gametes. We evaluated the effects of a model environmental estrogen, ethinyl estradiol (EE2), on the d-rR strain of medaka, Oryzias latipes, using a nano-injection exposure. Gonad histopathology...
Authors
Diana M. Papoulias, Douglas B. Noltie, Donald E. Tillitt
Science and Products
Filter Total Items: 215
Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure
This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish. A multitude of chemicals induce EROD activity in a variety of fish species, the most potent inducers being structural analogs of 2,3,7,8-tetracholordibenzo-p-dioxin...
Authors
J.J. Whyte, R.E. Jung, C. J. Schmitt, D. E. Tillitt
PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin
Adult walleye were collected from several locations in the Lower Fox River and Green Bay, Wisconsin (the assessment area) and two relatively uncontaminated reference locations (Lake Winnebago and Patten Lake, Wisconsin) between July and October in 1996 and 1997. Whole body and liver samples collected in 1996 were analyzed for total PCBs, PCB congeners, and liver histological lesions...
Authors
Mace G. Barron, Michael J. Anderson, Dave Cacela, Joshua Lipton, Swee J. Teh, David E. Hinton, Judith T. Zelikoff, Audrey L. Dikkeboom, Donald E. Tillitt, Mark Holey, Nancy Denslow
Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems
This document describes the suite of biological methods of the U.S. Geological Survey- Biomonitoring of Environmental Status and Trends program for monitoring chemical contaminants and their effects on fish. The methods, which were selected by panels of experts, are being field-tested in rivers of the Mississippi River, Columbia River, and Rio Grande basins. General health biomarkers...
Authors
Vicki S. Blazer, Nancy D. Denslow, Gail M. Dethloff, Timothy S. Gross, Kelly K. McDonald, Christopher J. Schmitt, Donald E. Tillitt, Jeffrey J. Whyte
Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts
The analysis of PCBs in fish tissues by immunoassay methods was evaluated using fish collected from a US monitoring program, the National Contaminant Biomonitoring Program of the US Department of Interior, Fish and Wildlife Service. Selected composite whole fish samples, which represented widely varying concentrations and sources of PCBs, were extracted and subjected to congener PCB...
Authors
J.L. Zajicek, D. E. Tillitt, T.R. Schwartz, C. J. Schmitt, R.O. Harrison
Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment
Polychlorinated naphthalenes (PCNs) are organic compounds with some chemical properties and uses similar to polychlorinated biphenyls. Polychlorinated naphthalenes have been detected in biota from certain aquatic environments. The toxicities of several PCN technical mixtures (Halowax) to medaka (Oryzias latipes) were determined by use of an embryo nanoinjection method. Medaka eggs (early...
Authors
Sergio A. Villalobos, Diana M. Papoulias, John C. Meadows, Alan L. Blankenship, Stephanie D. Pastva, Kurunthachalam Kannan, D.E. Hinton, Donald E. Tillitt, John P. Giesy
An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol
A model system was characterized which may be used as an in vivo screen for effects of chemicals or environmental mixtures on sexual differentiation and development of reproductive organs and gametes. We evaluated the effects of a model environmental estrogen, ethinyl estradiol (EE2), on the d-rR strain of medaka, Oryzias latipes, using a nano-injection exposure. Gonad histopathology...
Authors
Diana M. Papoulias, Douglas B. Noltie, Donald E. Tillitt
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government