Elizabeth Falendysz (Former Employee)
Science and Products
Filter Total Items: 14
Attenuation of monkeypox virus by deletion of genomic regions Attenuation of monkeypox virus by deletion of genomic regions
Monkeypox virus (MPXV) is an emerging pathogen from Africa that causes disease similar to smallpox. Two clades with different geographic distributions and virulence have been described. Here, we utilized bioinformatic tools to identify genomic regions in MPXV containing multiple virulence genes and explored their roles in pathogenicity; two selected regions were then deleted singularly...
Authors
Juan Lopera, Elizabeth Falendysz, Tonie Rocke, Jorge E. Osorio
Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging
Monkeypox (MPX) is a re-emerging zoonotic disease that is endemic in Central and West Africa, where it can cause a smallpox-like disease in humans. Despite many epidemiologic and field investigations of MPX, no definitive reservoir species has been identified. Using recombinant viruses expressing the firefly luciferase (luc) gene, we previously demonstrated the suitability of in vivo...
Authors
Elizabeth A. Falendysz, Angela Londono-Navas, Carol Meteyer, Nicola Pussini, Juan Lopera, Jorge E. Osorio, Tonie Rocke
Non-USGS Publications**
Salzer JS, Carroll DS, Rwego IB, Li Y, Falendysz EA; Shisler JL, Karem KL, Damon IK, Gillespie TR. Serologic evidence for circulating orthopoxviruses in peridomestic rodents from rural Uganda. Journal of Wildlife Disease. 2013. 49(1):125-31.
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
Science and Products
Filter Total Items: 14
Attenuation of monkeypox virus by deletion of genomic regions Attenuation of monkeypox virus by deletion of genomic regions
Monkeypox virus (MPXV) is an emerging pathogen from Africa that causes disease similar to smallpox. Two clades with different geographic distributions and virulence have been described. Here, we utilized bioinformatic tools to identify genomic regions in MPXV containing multiple virulence genes and explored their roles in pathogenicity; two selected regions were then deleted singularly...
Authors
Juan Lopera, Elizabeth Falendysz, Tonie Rocke, Jorge E. Osorio
Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging
Monkeypox (MPX) is a re-emerging zoonotic disease that is endemic in Central and West Africa, where it can cause a smallpox-like disease in humans. Despite many epidemiologic and field investigations of MPX, no definitive reservoir species has been identified. Using recombinant viruses expressing the firefly luciferase (luc) gene, we previously demonstrated the suitability of in vivo...
Authors
Elizabeth A. Falendysz, Angela Londono-Navas, Carol Meteyer, Nicola Pussini, Juan Lopera, Jorge E. Osorio, Tonie Rocke
Non-USGS Publications**
Salzer JS, Carroll DS, Rwego IB, Li Y, Falendysz EA; Shisler JL, Karem KL, Damon IK, Gillespie TR. Serologic evidence for circulating orthopoxviruses in peridomestic rodents from rural Uganda. Journal of Wildlife Disease. 2013. 49(1):125-31.
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government