Five Year Stability Study of Lampricides
Lampricides are usually ordered and produced in large quantities every two or three years depending on projected need. The majority of the lampricides are used within three years. The chemical stability of lampricides stored under normal standard operating procedures is not known beyond three years. Product that has been stored for more than 3 years has to be tested for percent active ingredient or discarded. To avoid the extra cost associated with retesting or discarding older lampricides it would be beneficial to have stability data that covers the maximum conceivable storage period for each lampricide. Most of the lampricides are stored in three facilities (Ludington, Ml; Marquette, Ml; and Sault Ste. Marie, ON, Canada). The temperature and humidity within the Ludington and Sault Ste. Marie storage facilities are relatively constant (controlled). At the Marquette facility the temperature and humidity vary with the season (uncontrolled). It is not known if the storage environment affects the long term stability of the lampricides.
Objective
1. The objective of this study is to monitor lampricides that are stored in temperature and humidity controlled and uncontrolled facilities for change in active ingredient concentration through a 5 year period.
References
40 CFR Part 160, Good Laboratory Practice Standards. 40 CFR Ch. I (7-1-15 Edition)
Bates, Douglas, Martin Maechler, Ben Bolker, Steve Walker (2015). Fitting Linear Mixed-Effects Models
Using lme4. Journal of Statistical Software, 67(1), 1-48. doi:10.18637/jss.v067.i01.
Bolker, Benjamin M. Ecological models and data in R. Princeton University Press, 2008.
EPA 712-C-02-026, June 2002
GLFC AOP: 006.4 - Policy for the Acquisition and Maintenance of an Inventory of Lampricide Stocks.
(Great Lakes Fishery Commission Integrated Management of Sea Lamprey (Petromyzon marinus)
Control Program)
R Core Team (2016). R: A language and environment for statistical computing. R Foundation for
Statistical Computing, Vienna, Austria. URL https://www.R-project.org/.
Lampricides are usually ordered and produced in large quantities every two or three years depending on projected need. The majority of the lampricides are used within three years. The chemical stability of lampricides stored under normal standard operating procedures is not known beyond three years. Product that has been stored for more than 3 years has to be tested for percent active ingredient or discarded. To avoid the extra cost associated with retesting or discarding older lampricides it would be beneficial to have stability data that covers the maximum conceivable storage period for each lampricide. Most of the lampricides are stored in three facilities (Ludington, Ml; Marquette, Ml; and Sault Ste. Marie, ON, Canada). The temperature and humidity within the Ludington and Sault Ste. Marie storage facilities are relatively constant (controlled). At the Marquette facility the temperature and humidity vary with the season (uncontrolled). It is not known if the storage environment affects the long term stability of the lampricides.
Objective
1. The objective of this study is to monitor lampricides that are stored in temperature and humidity controlled and uncontrolled facilities for change in active ingredient concentration through a 5 year period.
References
40 CFR Part 160, Good Laboratory Practice Standards. 40 CFR Ch. I (7-1-15 Edition)
Bates, Douglas, Martin Maechler, Ben Bolker, Steve Walker (2015). Fitting Linear Mixed-Effects Models
Using lme4. Journal of Statistical Software, 67(1), 1-48. doi:10.18637/jss.v067.i01.
Bolker, Benjamin M. Ecological models and data in R. Princeton University Press, 2008.
EPA 712-C-02-026, June 2002
GLFC AOP: 006.4 - Policy for the Acquisition and Maintenance of an Inventory of Lampricide Stocks.
(Great Lakes Fishery Commission Integrated Management of Sea Lamprey (Petromyzon marinus)
Control Program)
R Core Team (2016). R: A language and environment for statistical computing. R Foundation for
Statistical Computing, Vienna, Austria. URL https://www.R-project.org/.