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Viral loads, histology, and adverse events in transgenic mice after passive transfer of serum from black-footed ferrets (Mustela nigripes) used to assess the anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate

October 11, 2022

This data set provides biological information from of a captive study of transgenic mice that received either passive serum transfers from black-footed ferrets (BFFs) that were vaccinated against SARS-CoV-2 or BFFs that were unvaccinated, or a monoclonal antibody against SARS-CoV-2 or lastly a placebo. After these treatments mice were challenged with SARS-CoV-2. The data included here have viral loads in the lungs of treated mice, as well as histological results from various tissues collected at the end of the study.

Publication Year 2022
Title Viral loads, histology, and adverse events in transgenic mice after passive transfer of serum from black-footed ferrets (Mustela nigripes) used to assess the anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate
DOI 10.5066/P9GZEXN9
Authors Ariel E Leon, Della Garelle, Airn Hartwig, Elizabeth A Falendysz, Hon S Ip, Julia S Lankton, Tyler N Tretten, Terry Spraker, Richard Bowen, Tonie E Rocke
Product Type Data Release
Record Source USGS Asset Identifier Service (AIS)
USGS Organization National Wildlife Health Center
Rights This work is marked with CC0 1.0 Universal
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