What causes chronic wasting disease?
Chronic wasting disease is caused by a misfolded protein called a prion. All mammals produce normal prions that are used by cells, then degraded and eliminated, or recycled, within the body. When disease-associated prions contact normal prions, they cause them to refold into their own abnormal shape. These disease-associated prions are not readily broken down and tend to accumulate in--and damage--lymphatic and neural tissues, including the brain.
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Filter Total Items: 17
Ungulate migrations of the western United States, volume 3 Ungulate migrations of the western United States, volume 3
Ungulates (hooved mammals) have a broad distribution across the western United States and play an important role in maintaining predator-prey dynamics, affecting vegetation communities, and providing economic benefits to regional communities through tourism and hunting. Throughout the diverse landscapes they occupy, many ungulate populations undertake seasonal migrations to exploit...
Authors
Matthew Kauffman, Blake Lowrey, Jodi Berg, Scott Bergen, Doug Brimeyer, Patrick Burke, Teal Cufaude, James W. Cain, Jeffrey Cole, Alyson Courtemanch, Michelle Cowardin, Julie Cunningham, Melia DeVivo, Jennifer Diamond, Orrin Duvuvuei, Julien Fattebert, Joanna R. Ennis, Darby Finley, Jessica Fort, Gary Fralick, Eric Freeman, Jeff Gagnon, Julie Garcia, Emily Gelzer, Morgan Graham, Jacob Gray, Evan Greenspan, L. Embere Hall, Curtis Hendricks, Andy Holland, Brian Holmes, Katey Huggler, Mark A. Hurley, Emily Jeffreys, Aran Johnson, Lee Knox, Kevin Krasnow, Zack Lockyer, Hannah Manninen, Mike McDonald, Jennifer L. McKee, James Meacham, Jerod Merkle, Barb Moore, Tony W. Mong, Clayton Nielsen, Brendan Oates, Kim Olsen, Daniel Olson, Lucas Olson, Matt Pieron, Jake Powell, Annemarie Prince, Kelly Proffitt, Craig Reddell, Corinna Riginos, Robert Ritson, Sierra Robatcek, Shane Roberts, Hall Sawyer, Cody Schroeder, Jessie Shapiro, Nova Simpson, Scott Sprague, Alethea Steingisser, Nicole Tatman, Benjamin Turnock, Cody F. Wallace, Laura Wolf
The economic costs of chronic wasting disease in the United States The economic costs of chronic wasting disease in the United States
Cervids are economically important to a wide range of stakeholders and rights holders in the United States. The continued expansion of chronic wasting disease (CWD), a fatal neurodegenerative disease affecting wild and farmed cervids, poses a direct and indirect threat to state and federal government agency operations and cervid related economic activity. However, the scale of this...
Authors
Scott J. Chiavacci
Chronic wasting disease—Research by the U.S. Geological Survey and partners Chronic wasting disease—Research by the U.S. Geological Survey and partners
Introduction Chronic wasting disease (CWD) is the only transmissible spongiform encephalopathy, a class of invariably fatal neurodegenerative mammalian diseases associated with a misfolded cellular prion protein found in wild free-ranging animals. Because it has a long incubation period, affected animals in Cervidae (the deer family; referred to as “cervids”) may not show signs of...
Authors
M. Camille Hopkins, Christina M. Carlson, Paul C. Cross, Christopher J. Johnson, Bryan J. Richards, Robin E. Russell, Michael D. Samuel, Glen A. Sargeant, Daniel P. Walsh, W. David Walter
U.S. Geological Survey response to chronic wasting disease U.S. Geological Survey response to chronic wasting disease
The U.S. Geological Survey (USGS) is focused on the development of early detection and effective response tools that promote an adaptive management approach to chronic wasting disease (CWD). USGS scientists across the United States are working to understand the biology of CWD, assess and predict the spread and persistence in wildlife and the environment, and develop tools for early...
Authors
M. Camille Hopkins, Suzanna C. Soileau
Chronic wasting disease—Status, science, and management support by the U.S. Geological Survey Chronic wasting disease—Status, science, and management support by the U.S. Geological Survey
The U.S. Geological Survey (USGS) investigates chronic wasting disease (CWD) at multiple science centers and cooperative research units across the Nation and supports the management of CWD through science-based strategies. CWD research conducted by USGS scientists has three strategies: (1) to understand the biology, ecology, and causes and distribution of CWD; (2) to assess and predict...
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Christina M. Carlson, M. Camille Hopkins, Natalie T. Nguyen, Bryan J. Richards, Daniel P. Walsh, W. David Walter
Field Manual of Wildlife Diseases Field Manual of Wildlife Diseases
Welcome to a new version of the “Field Manual of Wildlife Diseases.” Unlike the previous printed versions of this publication, this new version is being developed as a “living“ electronic publication. Content will periodically be added and (or) updated as warranted, and it will always be reviewed by scientific experts (“peer reviewed”) before it is released. Thus, this publication will...
Related
Filter Total Items: 17
Ungulate migrations of the western United States, volume 3 Ungulate migrations of the western United States, volume 3
Ungulates (hooved mammals) have a broad distribution across the western United States and play an important role in maintaining predator-prey dynamics, affecting vegetation communities, and providing economic benefits to regional communities through tourism and hunting. Throughout the diverse landscapes they occupy, many ungulate populations undertake seasonal migrations to exploit...
Authors
Matthew Kauffman, Blake Lowrey, Jodi Berg, Scott Bergen, Doug Brimeyer, Patrick Burke, Teal Cufaude, James W. Cain, Jeffrey Cole, Alyson Courtemanch, Michelle Cowardin, Julie Cunningham, Melia DeVivo, Jennifer Diamond, Orrin Duvuvuei, Julien Fattebert, Joanna R. Ennis, Darby Finley, Jessica Fort, Gary Fralick, Eric Freeman, Jeff Gagnon, Julie Garcia, Emily Gelzer, Morgan Graham, Jacob Gray, Evan Greenspan, L. Embere Hall, Curtis Hendricks, Andy Holland, Brian Holmes, Katey Huggler, Mark A. Hurley, Emily Jeffreys, Aran Johnson, Lee Knox, Kevin Krasnow, Zack Lockyer, Hannah Manninen, Mike McDonald, Jennifer L. McKee, James Meacham, Jerod Merkle, Barb Moore, Tony W. Mong, Clayton Nielsen, Brendan Oates, Kim Olsen, Daniel Olson, Lucas Olson, Matt Pieron, Jake Powell, Annemarie Prince, Kelly Proffitt, Craig Reddell, Corinna Riginos, Robert Ritson, Sierra Robatcek, Shane Roberts, Hall Sawyer, Cody Schroeder, Jessie Shapiro, Nova Simpson, Scott Sprague, Alethea Steingisser, Nicole Tatman, Benjamin Turnock, Cody F. Wallace, Laura Wolf
The economic costs of chronic wasting disease in the United States The economic costs of chronic wasting disease in the United States
Cervids are economically important to a wide range of stakeholders and rights holders in the United States. The continued expansion of chronic wasting disease (CWD), a fatal neurodegenerative disease affecting wild and farmed cervids, poses a direct and indirect threat to state and federal government agency operations and cervid related economic activity. However, the scale of this...
Authors
Scott J. Chiavacci
Chronic wasting disease—Research by the U.S. Geological Survey and partners Chronic wasting disease—Research by the U.S. Geological Survey and partners
Introduction Chronic wasting disease (CWD) is the only transmissible spongiform encephalopathy, a class of invariably fatal neurodegenerative mammalian diseases associated with a misfolded cellular prion protein found in wild free-ranging animals. Because it has a long incubation period, affected animals in Cervidae (the deer family; referred to as “cervids”) may not show signs of...
Authors
M. Camille Hopkins, Christina M. Carlson, Paul C. Cross, Christopher J. Johnson, Bryan J. Richards, Robin E. Russell, Michael D. Samuel, Glen A. Sargeant, Daniel P. Walsh, W. David Walter
U.S. Geological Survey response to chronic wasting disease U.S. Geological Survey response to chronic wasting disease
The U.S. Geological Survey (USGS) is focused on the development of early detection and effective response tools that promote an adaptive management approach to chronic wasting disease (CWD). USGS scientists across the United States are working to understand the biology of CWD, assess and predict the spread and persistence in wildlife and the environment, and develop tools for early...
Authors
M. Camille Hopkins, Suzanna C. Soileau
Chronic wasting disease—Status, science, and management support by the U.S. Geological Survey Chronic wasting disease—Status, science, and management support by the U.S. Geological Survey
The U.S. Geological Survey (USGS) investigates chronic wasting disease (CWD) at multiple science centers and cooperative research units across the Nation and supports the management of CWD through science-based strategies. CWD research conducted by USGS scientists has three strategies: (1) to understand the biology, ecology, and causes and distribution of CWD; (2) to assess and predict...
Authors
Christina M. Carlson, M. Camille Hopkins, Natalie T. Nguyen, Bryan J. Richards, Daniel P. Walsh, W. David Walter
Field Manual of Wildlife Diseases Field Manual of Wildlife Diseases
Welcome to a new version of the “Field Manual of Wildlife Diseases.” Unlike the previous printed versions of this publication, this new version is being developed as a “living“ electronic publication. Content will periodically be added and (or) updated as warranted, and it will always be reviewed by scientific experts (“peer reviewed”) before it is released. Thus, this publication will...
Updated Date: January 15, 2026