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Air pollution and respiratory hospital admissions in Shiraz, Iran, 2009 to 2015

August 16, 2019

Air pollution has been identified as one of the most challenging health issues in urban areas worldwide.

The aim of this study was to investigate the association between short-term exposure to ambient air pollution and respiratory disease over a long-term period in Shiraz, one of the largest cities in Iran. Methods: hospital admissions due to respiratory diseases (asthma, pneumonia, chronic obstructive pulmonary disease(COPD) and pleural effusion) in residents of Shiraz between March 21, 2009 and March 20, 2015 were included. Demographics for each patient and meta data to include principal meteorological variables (temperature and relative humidity) and five ambient pollutants (CO, O3, SO2, NO2, and PM10) were also included. Statistical analysis was performed by Poisson regression in single-pollutant generalized linear model with principal component analysis (GLPCA) to analyze the relationship between pollutants and hospital admissions at the 0–9 cumulative lag day period. Pearson correlation test was used to determine the relationship between different pollutants, temperature and humidity.


It was found that the highest increase in asthma admission was related to PM10(relative risk (RR) = 1.31, 95% CI = 1.17, 1.47). For COPD, the rate of hospital visits significantly increased with the increase in NO2 concentration (RR = 1.17, 95% CI = In the children's hospital, O3 (RR = 1.25, 95% CI = 1.06, 1.47) and SO2(RR = 1.17, 95% CI = 1.07, 1.28) affected the asthma admissions and all contaminants (highest RR observed was for NO2 (RR = 1.28 95% CI = 1.18, 1.40) affected pneumonia admissions on cumulative lag days of 0–9. Conclusions: These data confirm an association between ambient air pollutants and hospital admissions due to respiratory disease.

Publication Year 2019
Title Air pollution and respiratory hospital admissions in Shiraz, Iran, 2009 to 2015
DOI 10.1016/j.atmosenv.2019.04.030
Authors Zahra Soleimani, Ali Darvishi Boloorani, Reza Khalifeh, Pari Teymouri, Alireza Mesdaghinia, Dale W. Griffin
Publication Type Article
Publication Subtype Journal Article
Series Title Atmospheric Environment
Index ID 70205015
Record Source USGS Publications Warehouse
USGS Organization St. Petersburg Coastal and Marine Science Center