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Characterization and expression profile of the ovarian cytochrome P-450 aromatase (cyp19A1) gene during thermolabile sex determination in Pejerrey, Odontesthes bonariensis

January 1, 2007

Cytochrome P450 aromatase (cyp19) is an enzyme that catalyzes the conversion of androgens to estrogens and may play a role in temperature- dependent sex determination (TSD) of reptiles, amphibians, and fishes. In this study, the ovarian P450 aromatase form (cyp19A1) of pejerrey Odontesthes bonariensis, a teleost with marked TSD, was cloned and its expression profile evaluated during gonadal differentiation at feminizing (17??C, 100% females), mixed-sex producing (24 and 25??C, 73.3 and 26.7% females, respectively), and masculinizing (29??C, 0% females) temperatures. The deduced cyp19A1 amino acid sequence shared high identity (>77.8%) with that from other teleosts but had low identity (

Publication Year 2007
Title Characterization and expression profile of the ovarian cytochrome P-450 aromatase (cyp19A1) gene during thermolabile sex determination in Pejerrey, Odontesthes bonariensis
DOI 10.1002/jez.416
Authors M. Karube, J.I. Fernandino, P. Strobl-Mazzulla, C.A. Strussmann, G. Yoshizaki, G.M. Somoza, R. Patino
Publication Type Article
Publication Subtype Journal Article
Series Title Journal of Experimental Zoology Part A: Ecological Genetics and Physiology
Index ID 70031316
Record Source USGS Publications Warehouse
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