Characterization and expression profile of the ovarian cytochrome P-450 aromatase (cyp19A1) gene during thermolabile sex determination in Pejerrey, Odontesthes bonariensis
Cytochrome P450 aromatase (cyp19) is an enzyme that catalyzes the conversion of androgens to estrogens and may play a role in temperature- dependent sex determination (TSD) of reptiles, amphibians, and fishes. In this study, the ovarian P450 aromatase form (cyp19A1) of pejerrey Odontesthes bonariensis, a teleost with marked TSD, was cloned and its expression profile evaluated during gonadal differentiation at feminizing (17??C, 100% females), mixed-sex producing (24 and 25??C, 73.3 and 26.7% females, respectively), and masculinizing (29??C, 0% females) temperatures. The deduced cyp19A1 amino acid sequence shared high identity (>77.8%) with that from other teleosts but had low identity (
Citation Information
| Publication Year | 2007 |
|---|---|
| Title | Characterization and expression profile of the ovarian cytochrome P-450 aromatase (cyp19A1) gene during thermolabile sex determination in Pejerrey, Odontesthes bonariensis |
| DOI | 10.1002/jez.416 |
| Authors | M. Karube, J.I. Fernandino, P. Strobl-Mazzulla, C.A. Strussmann, G. Yoshizaki, G.M. Somoza, R. Patino |
| Publication Type | Article |
| Publication Subtype | Journal Article |
| Series Title | Journal of Experimental Zoology Part A: Ecological Genetics and Physiology |
| Index ID | 70031316 |
| Record Source | USGS Publications Warehouse |