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Limited infection upon human exposure to a recombinant raccoon pox vaccine vector

January 1, 2004

A laboratory accident resulted in human exposure to a recombinant raccoon poxvirus (RCN) developed as a vaccine vector for antigens of Yersinia pestis for protection of wild rodents (and other animals) against plague. Within 9 days, the patient developed a small blister that healed within 4 weeks. Raccoon poxvirus was cultured from the lesion, and the patient developed antibody to plague antigen (F1) and RCN. This is the first documented case of human exposure to RCN.

Citation Information

Publication Year 2004
Title Limited infection upon human exposure to a recombinant raccoon pox vaccine vector
DOI 10.1016/j.vaccine.2004.01.030
Authors T.E. Rocke, F. J. Dein, M. Fuchsberger, B.C. Fox, D.T. Stinchcomb, J.G. Osorio
Publication Type Article
Publication Subtype Journal Article
Series Title Vaccine
Index ID 1003795
Record Source USGS Publications Warehouse
USGS Organization National Wildlife Health Center

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