Five species of riparian vertebrates (425 individuals) primarily representing upper trophic levels were collected from the Big River and Black River drainages in two lead mining districts of southeastern Missouri, 1981–82. Big River is subject to metal pollution via erosion and seepage from large tailings piles from inactive lead mines. Black River drains part of a currently mined area. Bullfrogs (Rana catesbeiana), muskrats (Ondatra zibethicus), and green-backed herons (Butorides striatus) collected downstream from the source of metal contamination to Big River had significantly (ANOVA, P