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Toxicogenomics in regulatory ecotoxicology

July 1, 2006

Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has become a rapidly growing topical area in multiple biological disciplines. Since 1999, when the term “toxicogenomics” was coined to describe the application of genomics to toxicology (1), a rapid increase in publications on the topic has occurred (Figure 1). The potential utility of toxicogenomics in toxicological research and regulatory activities has been the subject of scientific discussions and, as with any new technology, has evoked a wide range of opinion (2–6).

Citation Information

Publication Year 2006
Title Toxicogenomics in regulatory ecotoxicology
DOI 10.1021/es0630184
Authors Gerald T. Ankley, George P. Daston, Sigmund J. Degitz, Nancy D. Denslow, Robert A. Hoke, Sean W. Kennedy, Ann L. Miracle, Edward J. Perkins, Jason Snape, Donald E. Tillitt, Charles R. Tyler, Donald Versteeg
Publication Type Article
Publication Subtype Journal Article
Series Title Environmental Science & Technology
Series Number
Index ID 70171562
Record Source USGS Publications Warehouse
USGS Organization Columbia Environmental Research Center