Tonie Rocke
Tonie Rocke is a Research Epidemiologist at the National Wildlife Health Center.
Science and Products
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Recombinant raccoon pox vaccine protects mice against lethal plague Recombinant raccoon pox vaccine protects mice against lethal plague
Using a raccoon poxvirus (RCN) expression system, we have developed new recombinant vaccines that can protect mice against lethal plague infection. We tested the effects of a translation enhancer (EMCV-IRES) in combination with a secretory (tPA) signal or secretory (tPA) and membrane anchoring (CHV-gG) signals on in vitro antigen expression of F1 antigen in tissue culture and the...
Authors
J.E. Osorio, T.D. Powell, R.S. Frank, K. Moss, E.J. Haanes, S.R. Smith, Tonie E. Rocke, D.T. Stinchcomb
Determination of the median toxic dose of type C botulism in lactating dairy cows Determination of the median toxic dose of type C botulism in lactating dairy cows
Because of the difficulty in identifying botulinum toxin in cattle, it is hypothesized that cattle are sensitive to levels of toxin below the detection limits of current diagnostic techniques (the mouse protection bioassay and the immunostick enzyme-linked immunosorbent assay [ELISA] for type C botulinum toxin). Using an up-down method for toxicologic testing, the median toxic dose...
Authors
R.B. Moeller, B. Puschner, R.L. Walker, Tonie E. Rocke, F.D. Galey, J.S. Cullor, A.A. Ardans
New host record of avian tuberculosis in an American white pelican, Pelecanus erythrorhynchos New host record of avian tuberculosis in an American white pelican, Pelecanus erythrorhynchos
An American white pelican (P. erythrorhyncos) was captured in August 1999 in California, USA. The bird was unable to fly away or evade the boat, and showed considerable aggression when captured. Numerous multifocal, 1 mm diameter, yellow masses were observed throughout the lungs and air sacs. The liver was yellow. A 6 cm diameter, firm spherical mass was present in the abdominal cavity...
Authors
P. Nol, R.E. Brannian, B.M. Berlowski, M. J. Wolcott, Tonie E. Rocke
Failure to transmit avian vacuolar myelinopathy to mallard ducks Failure to transmit avian vacuolar myelinopathy to mallard ducks
Avian vacuolar myelinopathy (AVM) is a neurologic disease that has been diagnosed in free-ranging birds in the southeastern United States. Bald eagles (Haliaeetus leuocephalus), American coots (Fulica americana), and mallards (Anas platyrhynchos) have been affected. Previous investigations have not determined the etiology of this disease. In November and December 2002, we attempted to...
Authors
R. S. Larsen, Felicia B. Nutter, Tom Augspurger, Tonie E. Rocke, Nancy J. Thomas, Michael K. Stoskopf
Vacuolar myelinopathy in waterfowl from a North Carolina impoundment Vacuolar myelinopathy in waterfowl from a North Carolina impoundment
Vacuolar myelinopathy was confirmed by light and electron microscopic examination of mallards (Anas platyrhynchos), ring-necked ducks (Aythya collaris), and buffleheads (Bucephala albeola) collected during an epizootic at Lake Surf in central North Carolina (USA) between November 1998 and February 1999. Clinical signs of affected birds were consistent with central nervous system...
Authors
T. Augspurger, John R. Fischer, Nancy Thomas, L. Sileo, Roger E. Brannian, Kimberli J.G. Miller, Tonie E. Rocke
Joining forces to improve our world Joining forces to improve our world
No abstract available.
Authors
W.B. Karesh, S.A. Osofsky, Tonie E. Rocke, P.L. Barrows
Science and Products
Filter Total Items: 16
No Result Found
Filter Total Items: 134
Recombinant raccoon pox vaccine protects mice against lethal plague Recombinant raccoon pox vaccine protects mice against lethal plague
Using a raccoon poxvirus (RCN) expression system, we have developed new recombinant vaccines that can protect mice against lethal plague infection. We tested the effects of a translation enhancer (EMCV-IRES) in combination with a secretory (tPA) signal or secretory (tPA) and membrane anchoring (CHV-gG) signals on in vitro antigen expression of F1 antigen in tissue culture and the...
Authors
J.E. Osorio, T.D. Powell, R.S. Frank, K. Moss, E.J. Haanes, S.R. Smith, Tonie E. Rocke, D.T. Stinchcomb
Determination of the median toxic dose of type C botulism in lactating dairy cows Determination of the median toxic dose of type C botulism in lactating dairy cows
Because of the difficulty in identifying botulinum toxin in cattle, it is hypothesized that cattle are sensitive to levels of toxin below the detection limits of current diagnostic techniques (the mouse protection bioassay and the immunostick enzyme-linked immunosorbent assay [ELISA] for type C botulinum toxin). Using an up-down method for toxicologic testing, the median toxic dose...
Authors
R.B. Moeller, B. Puschner, R.L. Walker, Tonie E. Rocke, F.D. Galey, J.S. Cullor, A.A. Ardans
New host record of avian tuberculosis in an American white pelican, Pelecanus erythrorhynchos New host record of avian tuberculosis in an American white pelican, Pelecanus erythrorhynchos
An American white pelican (P. erythrorhyncos) was captured in August 1999 in California, USA. The bird was unable to fly away or evade the boat, and showed considerable aggression when captured. Numerous multifocal, 1 mm diameter, yellow masses were observed throughout the lungs and air sacs. The liver was yellow. A 6 cm diameter, firm spherical mass was present in the abdominal cavity...
Authors
P. Nol, R.E. Brannian, B.M. Berlowski, M. J. Wolcott, Tonie E. Rocke
Failure to transmit avian vacuolar myelinopathy to mallard ducks Failure to transmit avian vacuolar myelinopathy to mallard ducks
Avian vacuolar myelinopathy (AVM) is a neurologic disease that has been diagnosed in free-ranging birds in the southeastern United States. Bald eagles (Haliaeetus leuocephalus), American coots (Fulica americana), and mallards (Anas platyrhynchos) have been affected. Previous investigations have not determined the etiology of this disease. In November and December 2002, we attempted to...
Authors
R. S. Larsen, Felicia B. Nutter, Tom Augspurger, Tonie E. Rocke, Nancy J. Thomas, Michael K. Stoskopf
Vacuolar myelinopathy in waterfowl from a North Carolina impoundment Vacuolar myelinopathy in waterfowl from a North Carolina impoundment
Vacuolar myelinopathy was confirmed by light and electron microscopic examination of mallards (Anas platyrhynchos), ring-necked ducks (Aythya collaris), and buffleheads (Bucephala albeola) collected during an epizootic at Lake Surf in central North Carolina (USA) between November 1998 and February 1999. Clinical signs of affected birds were consistent with central nervous system...
Authors
T. Augspurger, John R. Fischer, Nancy Thomas, L. Sileo, Roger E. Brannian, Kimberli J.G. Miller, Tonie E. Rocke
Joining forces to improve our world Joining forces to improve our world
No abstract available.
Authors
W.B. Karesh, S.A. Osofsky, Tonie E. Rocke, P.L. Barrows