Tonie Rocke
Tonie Rocke is a Research Epidemiologist at the National Wildlife Health Center.
Science and Products
Filter Total Items: 16
No Result Found
Filter Total Items: 134
Factors influencing uptake of sylvatic plague vaccine baits by prairie dogs Factors influencing uptake of sylvatic plague vaccine baits by prairie dogs
Sylvatic plague vaccine (SPV) is a virally vectored bait-delivered vaccine expressing Yersinia pestis antigens that can protect prairie dogs (Cynomys spp.) from plague and has potential utility as a management tool. In a large-scale 3-year field trial, SPV-laden baits containing the biomarker rhodamine B (used to determine bait consumption) were distributed annually at a rate of...
Authors
Rachel C. Abbott, Robin E. Russell, Katherine Richgels, Daniel W. Tripp, Marc R. Matchett, Dean E. Biggins, Tonie E. Rocke
Assessing monkeypox virus prevalence in small mammals at the human-animal interface in the Democratic Republic of the Congo Assessing monkeypox virus prevalence in small mammals at the human-animal interface in the Democratic Republic of the Congo
During 2012, 2013 and 2015, we collected small mammals within 25 km of the town of Boende in Tshuapa Province, the Democratic Republic of the Congo. The prevalence of monkeypox virus (MPXV) in this area is unknown; however, cases of human infection were previously confirmed near these collection sites. Samples were collected from 353 mammals (rodents, shrews, pangolins, elephant shrews...
Authors
Jeffrey B. Doty, Jean M. Malekani, Lem’s N. Kalemba, William T. Stanley, Benjamin P. Monroe, Yoshinori J. Nakazawa, Matthew R. Mauldin, Tresor L. Bakambana, Tobit Liyandja Dja Liyandja, Zachary Braden, Ryan Wallace, Divin V. Malekani, Andrea M. McCollum, Nadia Gallardo-Romero, Ashley Kondas, A. Townsend Peterson, Jorge E. Osorio, Tonie E. Rocke, Kevin L. Karem, Ginny L. Emerson, Darin S. Carroll
Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine
Rabies is an ancient neglected tropical disease that causes tens of thousands of human deaths and millions of cattle deaths annually. In order to develop a new vaccine for potential use in bats, a reservoir of rabies infection for humans and animals alike, an in silico antigen designer tool was used to create a mosaic glycoprotein (MoG) gene using available sequences from the rabies...
Authors
Ben Stading, James A. Ellison, William C. Carson, Panayampalli Subbian Satheshkumar, Tonie E. Rocke, Jorge E. Osorio
Burrow dusting or oral vaccination prevents plague-associated prairie dog colony collapse Burrow dusting or oral vaccination prevents plague-associated prairie dog colony collapse
Plague impacts prairie dogs (Cynomys spp.), the endangered black-footed ferret (Mustela nigripes) and other sensitive wildlife species. We compared efficacy of prophylactic treatments (burrow dusting with deltamethrin or oral vaccination with recombinant “sylvatic plague vaccine” [RCN-F1/V307]) to placebo treatment in black-tailed prairie dog (C. ludovicianus) colonies. Between 2013 and...
Authors
Daniel W. Tripp, Tonie E. Rocke, Jonathan P. Runge, Rachel C. Abbott, Michael W. Miller
Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.) Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.)
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle, including the natural host of the virus, remain unknown. African rope squirrels (Funisciurus spp.) are considered potential reservoirs...
Authors
Elizabeth Falendysz, Juan G. Lopera, Jeffrey B. Doty, Yoshinori J. Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem’s N. Kalemba, Monica Ronderos, Andres Meija, Jean M. Malekani, Kevin L. Karem, Darrin Caroll, Jorge E. Osorio, Tonie E. Rocke
Sylvatic plague vaccine partially protects prairie dogs (Cynomys spp.) in field trials Sylvatic plague vaccine partially protects prairie dogs (Cynomys spp.) in field trials
Sylvatic plague, caused by Yersinia pestis, frequently afflicts prairie dogs (Cynomys spp.), causing population declines and local extirpations. We tested the effectiveness of bait-delivered sylvatic plague vaccine (SPV) in prairie dog colonies on 29 paired placebo and treatment plots (1–59 ha in size; average 16.9 ha) in 7 western states from 2013 to 2015. We compared relative abundance...
Authors
Tonie E. Rocke, Daniel W. Tripp, Robin E. Russell, Rachel C. Abbott, Katherine Richgels, Marc R. Matchett, Dean E. Biggins, Randall Griebel, Greg Schroeder, Shaun M. Grassel, David R. Pipkin, Jennifer Cordova, Adam Kavalunas, Brian Maxfield, Jesse T. Boulerice, Michael W. Miller
Science and Products
Filter Total Items: 16
No Result Found
Filter Total Items: 134
Factors influencing uptake of sylvatic plague vaccine baits by prairie dogs Factors influencing uptake of sylvatic plague vaccine baits by prairie dogs
Sylvatic plague vaccine (SPV) is a virally vectored bait-delivered vaccine expressing Yersinia pestis antigens that can protect prairie dogs (Cynomys spp.) from plague and has potential utility as a management tool. In a large-scale 3-year field trial, SPV-laden baits containing the biomarker rhodamine B (used to determine bait consumption) were distributed annually at a rate of...
Authors
Rachel C. Abbott, Robin E. Russell, Katherine Richgels, Daniel W. Tripp, Marc R. Matchett, Dean E. Biggins, Tonie E. Rocke
Assessing monkeypox virus prevalence in small mammals at the human-animal interface in the Democratic Republic of the Congo Assessing monkeypox virus prevalence in small mammals at the human-animal interface in the Democratic Republic of the Congo
During 2012, 2013 and 2015, we collected small mammals within 25 km of the town of Boende in Tshuapa Province, the Democratic Republic of the Congo. The prevalence of monkeypox virus (MPXV) in this area is unknown; however, cases of human infection were previously confirmed near these collection sites. Samples were collected from 353 mammals (rodents, shrews, pangolins, elephant shrews...
Authors
Jeffrey B. Doty, Jean M. Malekani, Lem’s N. Kalemba, William T. Stanley, Benjamin P. Monroe, Yoshinori J. Nakazawa, Matthew R. Mauldin, Tresor L. Bakambana, Tobit Liyandja Dja Liyandja, Zachary Braden, Ryan Wallace, Divin V. Malekani, Andrea M. McCollum, Nadia Gallardo-Romero, Ashley Kondas, A. Townsend Peterson, Jorge E. Osorio, Tonie E. Rocke, Kevin L. Karem, Ginny L. Emerson, Darin S. Carroll
Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine Protection of bats (Eptesicus fuscus) against rabies following topical or oronasal exposure to a recombinant raccoon poxvirus vaccine
Rabies is an ancient neglected tropical disease that causes tens of thousands of human deaths and millions of cattle deaths annually. In order to develop a new vaccine for potential use in bats, a reservoir of rabies infection for humans and animals alike, an in silico antigen designer tool was used to create a mosaic glycoprotein (MoG) gene using available sequences from the rabies...
Authors
Ben Stading, James A. Ellison, William C. Carson, Panayampalli Subbian Satheshkumar, Tonie E. Rocke, Jorge E. Osorio
Burrow dusting or oral vaccination prevents plague-associated prairie dog colony collapse Burrow dusting or oral vaccination prevents plague-associated prairie dog colony collapse
Plague impacts prairie dogs (Cynomys spp.), the endangered black-footed ferret (Mustela nigripes) and other sensitive wildlife species. We compared efficacy of prophylactic treatments (burrow dusting with deltamethrin or oral vaccination with recombinant “sylvatic plague vaccine” [RCN-F1/V307]) to placebo treatment in black-tailed prairie dog (C. ludovicianus) colonies. Between 2013 and...
Authors
Daniel W. Tripp, Tonie E. Rocke, Jonathan P. Runge, Rachel C. Abbott, Michael W. Miller
Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.) Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.)
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle, including the natural host of the virus, remain unknown. African rope squirrels (Funisciurus spp.) are considered potential reservoirs...
Authors
Elizabeth Falendysz, Juan G. Lopera, Jeffrey B. Doty, Yoshinori J. Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem’s N. Kalemba, Monica Ronderos, Andres Meija, Jean M. Malekani, Kevin L. Karem, Darrin Caroll, Jorge E. Osorio, Tonie E. Rocke
Sylvatic plague vaccine partially protects prairie dogs (Cynomys spp.) in field trials Sylvatic plague vaccine partially protects prairie dogs (Cynomys spp.) in field trials
Sylvatic plague, caused by Yersinia pestis, frequently afflicts prairie dogs (Cynomys spp.), causing population declines and local extirpations. We tested the effectiveness of bait-delivered sylvatic plague vaccine (SPV) in prairie dog colonies on 29 paired placebo and treatment plots (1–59 ha in size; average 16.9 ha) in 7 western states from 2013 to 2015. We compared relative abundance...
Authors
Tonie E. Rocke, Daniel W. Tripp, Robin E. Russell, Rachel C. Abbott, Katherine Richgels, Marc R. Matchett, Dean E. Biggins, Randall Griebel, Greg Schroeder, Shaun M. Grassel, David R. Pipkin, Jennifer Cordova, Adam Kavalunas, Brian Maxfield, Jesse T. Boulerice, Michael W. Miller