Tonie Rocke
Tonie Rocke is a Research Epidemiologist at the National Wildlife Health Center.
Science and Products
Sylvatic Plague
Sylvatic plague, caused by Yersinia pestis, is a bacterial disease transmitted by fleas that afflicts many mammalian species, including humans.
White-Nose Syndrome
White-nose syndrome (WNS) is an emergent disease of hibernating bats that has spread from the northeastern across United States at an alarming rate.
Vector-Borne Diseases
Vector-borne diseases are transmitted from one animal to another by vectors, including insects, such as mosquitoes or fleas, and arachnids, such as ticks. The USGS National Wildlife Health Center investigates wildlife diseases, including vector-borne diseases, such as West Nile virus and sylvatic plague.
Filter Total Items: 16
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2 Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
We experimentally challenged wild Mexican free-tailed bats (TABR) with SARS-CoV-2 to determine the susceptibility, reservoir potential, and population impacts of infection in this species. Of nine bats oronasally inoculated with SARS-CoV-2, five became infected and orally excreted moderate amounts of virus for up to 18 days post inoculation. These five subjects all seroconverted and...
In vitro expression, immunogenicity, and efficacy data from recombinant raccoon poxvirus-vectored rabies vaccine candidates tested in mice In vitro expression, immunogenicity, and efficacy data from recombinant raccoon poxvirus-vectored rabies vaccine candidates tested in mice
This work is part of an experimental trial to develop and assess novel recombinant raccoonpox virus (RCN) rabies vaccines in the mouse model, for potential use in bats. Briefly, our research group previously developed a recombinant RCN vaccine candidate expressing a mosaic glycoprotein (MoG) gene that protected mice and big brown bats when challenged with rabies virus (RABV). We...
Data on Flea Parasitism and Annual Re-encounters of Utah Prairie Dogs at 5 colonies on the Awapa Plateau, Utah, USA, 2013-2016 Data on Flea Parasitism and Annual Re-encounters of Utah Prairie Dogs at 5 colonies on the Awapa Plateau, Utah, USA, 2013-2016
Data on flea parasitism and annual re-encounters of Utah prairie dogs at 5 colonies on the Awapa Plateau, Utah, USA, June-August 2013-2016. Utah prairie dogs were live-trapped and sampled on 5 colonies along an elevation gradient from 2,645 m to 2,873 m. Upon first capture each year, we anesthetized each prairie dog and fleas on its body and combed the prairie dog as thoroughly as...
Fleas collected from black-tailed prairie dog burrows in 2016 and 2017 Fleas collected from black-tailed prairie dog burrows in 2016 and 2017
The data are a list of the number and species of fleas that were collected from black-tailed prairie dog burrows in Montana, North Dakota, South Dakota, Colorado, and New Mexico. Fleas were collected by swabbing ~100 burrows at 3 sites at each of 6 sites. Burrows were sampled twice each summer during 2016 and 2017.
Survival of prairie dogs (Cynomys spp.) challenged with Yersina pestis (plague) Survival of prairie dogs (Cynomys spp.) challenged with Yersina pestis (plague)
These data represent the number of days a prairie dog survived after challenge with highly virulent Yeresinia pestis.
Sylvatic Plague Vaccine field trials flea data Sylvatic Plague Vaccine field trials flea data
hese data were collected as part of a field trial to test the efficacy of a sylvatic plague vaccine (see Rocke et al., 2017 for details). Vaccine and control plots were selected randomly from the available sites at each location. At least 1 week and no more than 2 months post-baiting each year, local collaborators captured, marked and sampled prairie dogs for a minimum of 3 trap days...
Filter Total Items: 134
Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir
Predicting the spatial occurrence of wildlife is a major challenge for ecology and management. In Latin America, limited knowledge of the number and locations of vampire bat roosts precludes informed allocation of measures intended to prevent rabies spillover to humans and livestock. We inferred the spatial distribution of vampire bat roosts while accounting for observation effort and
Authors
Rita Ribeiro, Jason Matthiopoulos, Finn Lindgre, Carlos Tello, Carlos M. Zariquiey, William Valderrama, Tonie E. Rocke, Daniel G. Streicker
Managing an ongoing threat: Bats and white-nose syndrome Managing an ongoing threat: Bats and white-nose syndrome
No abstract available.
Authors
Tricia Lynn Fry, Amy Haeseler, Anne Ballmann, Tonie E. Rocke
Management of vampire bats and rabies: Past, present, and future Management of vampire bats and rabies: Past, present, and future
Rabies virus transmitted via the bite of common vampire bats (Desmodus rotundus) has surpassed canine-associated cases as the predominant cause of human rabies in Latin America. Cattle, the preferred prey of D. rotundus, suffer extensive mortality from vampire bat associated rabies, with annual financial losses estimated in the tens of millions of dollars. Organized attempts to manage or...
Authors
Tonie E. Rocke, Daniel G. Streicker, Ariel Elizabeth Leon
Monkeypox virus in animals: Current knowledge of viral transmission and pathogenesis in wild animal reservoirs and captive animal models Monkeypox virus in animals: Current knowledge of viral transmission and pathogenesis in wild animal reservoirs and captive animal models
Mpox, formerly called monkeypox, is now the most serious orthopoxvirus (OPXV) infection in humans. This zoonotic disease has been gradually re-emerging in humans with an increasing frequency of cases found in endemic areas, as well as an escalating frequency and size of epidemics outside of endemic areas in Africa. Currently, the largest known mpox epidemic is spreading throughout the...
Authors
Elizabeth Falendysz, Juan G. Lopera, Tonie E. Rocke, Jorge E. Osorio
Sex-biased infections scale to population impacts for an emerging wildlife disease Sex-biased infections scale to population impacts for an emerging wildlife disease
Demographic factors are fundamental in shaping infectious disease dynamics. Aspects of populations that create structure, like age and sex, can affect patterns of transmission, infection intensity and population outcomes. However, studies rarely link these processes from individual to population-scale effects. Moreover, the mechanisms underlying demographic differences in disease are...
Authors
Macy J. Kailing, Joseph R. Hoyt, J. Paul White, Heather M. Kaarakka, Jennifer A. Redell, Ariel Elizabeth Leon, Tonie E. Rocke, John E. DePue, William H. Scullon, Katy L. Parise, Jeffrey T. Foster, A. Marm Kilpatrick, Kate E. Langwig
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2 Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus is thought to have originated in wild bats from Asia, and as the resulting pandemic continues into its third year, concerns have been raised that the virus will expand its host range and infect North American wildlife species, including bats. Mexican free-tailed bats (Tadarida brasiliensis) live in large colonies in...
Authors
Jeffrey S. Hall, Erik K. Hofmeister, Hon S. Ip, Sean Nashold, Ariel Elizabeth Leon, Carly Marie Malave, Elizabeth Falendysz, Tonie E. Rocke, M. Carossino, U. Balasuriya, Susan Knowles
Science and Products
Sylvatic Plague
Sylvatic plague, caused by Yersinia pestis, is a bacterial disease transmitted by fleas that afflicts many mammalian species, including humans.
White-Nose Syndrome
White-nose syndrome (WNS) is an emergent disease of hibernating bats that has spread from the northeastern across United States at an alarming rate.
Vector-Borne Diseases
Vector-borne diseases are transmitted from one animal to another by vectors, including insects, such as mosquitoes or fleas, and arachnids, such as ticks. The USGS National Wildlife Health Center investigates wildlife diseases, including vector-borne diseases, such as West Nile virus and sylvatic plague.
Filter Total Items: 16
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2 Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
We experimentally challenged wild Mexican free-tailed bats (TABR) with SARS-CoV-2 to determine the susceptibility, reservoir potential, and population impacts of infection in this species. Of nine bats oronasally inoculated with SARS-CoV-2, five became infected and orally excreted moderate amounts of virus for up to 18 days post inoculation. These five subjects all seroconverted and...
In vitro expression, immunogenicity, and efficacy data from recombinant raccoon poxvirus-vectored rabies vaccine candidates tested in mice In vitro expression, immunogenicity, and efficacy data from recombinant raccoon poxvirus-vectored rabies vaccine candidates tested in mice
This work is part of an experimental trial to develop and assess novel recombinant raccoonpox virus (RCN) rabies vaccines in the mouse model, for potential use in bats. Briefly, our research group previously developed a recombinant RCN vaccine candidate expressing a mosaic glycoprotein (MoG) gene that protected mice and big brown bats when challenged with rabies virus (RABV). We...
Data on Flea Parasitism and Annual Re-encounters of Utah Prairie Dogs at 5 colonies on the Awapa Plateau, Utah, USA, 2013-2016 Data on Flea Parasitism and Annual Re-encounters of Utah Prairie Dogs at 5 colonies on the Awapa Plateau, Utah, USA, 2013-2016
Data on flea parasitism and annual re-encounters of Utah prairie dogs at 5 colonies on the Awapa Plateau, Utah, USA, June-August 2013-2016. Utah prairie dogs were live-trapped and sampled on 5 colonies along an elevation gradient from 2,645 m to 2,873 m. Upon first capture each year, we anesthetized each prairie dog and fleas on its body and combed the prairie dog as thoroughly as...
Fleas collected from black-tailed prairie dog burrows in 2016 and 2017 Fleas collected from black-tailed prairie dog burrows in 2016 and 2017
The data are a list of the number and species of fleas that were collected from black-tailed prairie dog burrows in Montana, North Dakota, South Dakota, Colorado, and New Mexico. Fleas were collected by swabbing ~100 burrows at 3 sites at each of 6 sites. Burrows were sampled twice each summer during 2016 and 2017.
Survival of prairie dogs (Cynomys spp.) challenged with Yersina pestis (plague) Survival of prairie dogs (Cynomys spp.) challenged with Yersina pestis (plague)
These data represent the number of days a prairie dog survived after challenge with highly virulent Yeresinia pestis.
Sylvatic Plague Vaccine field trials flea data Sylvatic Plague Vaccine field trials flea data
hese data were collected as part of a field trial to test the efficacy of a sylvatic plague vaccine (see Rocke et al., 2017 for details). Vaccine and control plots were selected randomly from the available sites at each location. At least 1 week and no more than 2 months post-baiting each year, local collaborators captured, marked and sampled prairie dogs for a minimum of 3 trap days...
Filter Total Items: 134
Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir
Predicting the spatial occurrence of wildlife is a major challenge for ecology and management. In Latin America, limited knowledge of the number and locations of vampire bat roosts precludes informed allocation of measures intended to prevent rabies spillover to humans and livestock. We inferred the spatial distribution of vampire bat roosts while accounting for observation effort and
Authors
Rita Ribeiro, Jason Matthiopoulos, Finn Lindgre, Carlos Tello, Carlos M. Zariquiey, William Valderrama, Tonie E. Rocke, Daniel G. Streicker
Managing an ongoing threat: Bats and white-nose syndrome Managing an ongoing threat: Bats and white-nose syndrome
No abstract available.
Authors
Tricia Lynn Fry, Amy Haeseler, Anne Ballmann, Tonie E. Rocke
Management of vampire bats and rabies: Past, present, and future Management of vampire bats and rabies: Past, present, and future
Rabies virus transmitted via the bite of common vampire bats (Desmodus rotundus) has surpassed canine-associated cases as the predominant cause of human rabies in Latin America. Cattle, the preferred prey of D. rotundus, suffer extensive mortality from vampire bat associated rabies, with annual financial losses estimated in the tens of millions of dollars. Organized attempts to manage or...
Authors
Tonie E. Rocke, Daniel G. Streicker, Ariel Elizabeth Leon
Monkeypox virus in animals: Current knowledge of viral transmission and pathogenesis in wild animal reservoirs and captive animal models Monkeypox virus in animals: Current knowledge of viral transmission and pathogenesis in wild animal reservoirs and captive animal models
Mpox, formerly called monkeypox, is now the most serious orthopoxvirus (OPXV) infection in humans. This zoonotic disease has been gradually re-emerging in humans with an increasing frequency of cases found in endemic areas, as well as an escalating frequency and size of epidemics outside of endemic areas in Africa. Currently, the largest known mpox epidemic is spreading throughout the...
Authors
Elizabeth Falendysz, Juan G. Lopera, Tonie E. Rocke, Jorge E. Osorio
Sex-biased infections scale to population impacts for an emerging wildlife disease Sex-biased infections scale to population impacts for an emerging wildlife disease
Demographic factors are fundamental in shaping infectious disease dynamics. Aspects of populations that create structure, like age and sex, can affect patterns of transmission, infection intensity and population outcomes. However, studies rarely link these processes from individual to population-scale effects. Moreover, the mechanisms underlying demographic differences in disease are...
Authors
Macy J. Kailing, Joseph R. Hoyt, J. Paul White, Heather M. Kaarakka, Jennifer A. Redell, Ariel Elizabeth Leon, Tonie E. Rocke, John E. DePue, William H. Scullon, Katy L. Parise, Jeffrey T. Foster, A. Marm Kilpatrick, Kate E. Langwig
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2 Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus is thought to have originated in wild bats from Asia, and as the resulting pandemic continues into its third year, concerns have been raised that the virus will expand its host range and infect North American wildlife species, including bats. Mexican free-tailed bats (Tadarida brasiliensis) live in large colonies in...
Authors
Jeffrey S. Hall, Erik K. Hofmeister, Hon S. Ip, Sean Nashold, Ariel Elizabeth Leon, Carly Marie Malave, Elizabeth Falendysz, Tonie E. Rocke, M. Carossino, U. Balasuriya, Susan Knowles