Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) analyses of apatite provide trace element concentrations that support indicator mineral studies near the Taurus porphyry Cu-Mo deposit in the eastern Tanacross quadrangle, Alaska. The Taurus deposit and others in the region are mostly concealed, and traditional stream sediment samples typically show subdued geochemical signatures. The indicator mineral studies include collection of stream sediment samples and analysis using automated SEM mineralogical techniques. The presence of select minerals in the stream sediments may indicate mineralization. In addition, the chemistry of specific minerals may be used to distinguish a hydrothermal origin as opposed to others. The LA-ICP-MS data for apatite were collected by personnel of the Geology, Geophysics, and Geochemistry Science Center in Denver, Colorado, for the U.S. Geological Survey (USGS) Mineral Resources Program (MRP). Additional data were obtained at Queens University and Colorado School of Mines. Appreciable differences in chemistry were noted for apatite in mineralized rock and stream sediment samples draining these rocks compared to barren rocks or sediment samples away from mineralization.