Biomass production is positively correlated with mean tidal range in salt marshes along the Atlantic coast of the United States of America. Recent studies support the idea that enhanced stability of the marshes can be attributed to increased vegetative growth due to increased tidal range. This dataset displays the spatial variation of mean tidal range (i.e. Mean Range of Tides, MN) in the Cape Cod National Seashore (CACO) salt marsh complex and approximal wetlands based on conceptual marsh units defined by Defne and Ganju (2019). MN was based on the calculated difference in height between mean high water (MHW) and mean low water (MLW) using the VDatum (v3.5) database ( http://vdatum.noaa.gov/ ). Through scientific efforts initiated with the Hurricane Sandy Science Plan, the U.S. Geological Survey has been expanding national assessment of coastal change hazards and forecast products to coastal wetlands. The intent is to provide federal, state, and local managers with tools to estimate their vulnerability and ecosystem service potential. For this purpose, the response and resilience of coastal wetlands to physical factors need to be assessed in terms of the ensuing change to their vulnerability and ecosystem services. CACO is one of the selected domains to expand this study. References: Defne, Z., and Ganju, N.K., 2019, Conceptual marsh units for Cape Cod National Seashore salt marsh complex, Massachusetts: U.S. Geological Survey data release, https://doi.org/10.5066/P955K1Y2.