This dataset accompanies two proposed publications, "Descriptions and age constraints for new Jurassic flora fossils in west-central Sonora, Mexico: Results from U-Pb zircon geochronology, Sr-Nd isotopes, and megafossil taxa" and "Summary of Paleozoic and Mesozoic Rocks in Sonora and northern Sinaloa, Mexico", which will both report zircon SHRIMP-RG U-Pb ages and whole-rock isotope analyses. Samples were collected from the study area by Ricardo Amaya-Martinez and colleagues at the University of Sonora (Hermosillo) and Barney Poole (USGS), who brought them to the USGS Denver for analysis. The analyses were performed from 2004 to 2020.