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Field performance evaluation of a bayluscide 20-percent suspension concentrate formulation

March 19, 2026

Petromyzon marinus (sea lamprey) is a parasitic, invasive fish of the Laurentian Great Lakes. Since the late 1950s, the Great Lakes Fishery Commission has implemented an integrated Sea Lamprey Control Program (SLCP) that relies on two lampricidal chemicals: 3-(trifluoromethyl)-4-nitrophenol (TFM) and niclosamide. Niclosamide is applied using a bayluscide 20-percent emulsifiable concentrate; however, a solvent in this formulation, N-methyl-2-pyrrolidone, has been linked with worker safety concerns and has contributed to equipment degradation and clogging. To address these limitations, the U.S. Geological Survey, in collaboration with Battelle UK, developed a bayluscide 20-percent suspension concentrate (SC) as a potential alternative formulation.

In this study, we evaluated the field performance of SC on the Indian River in Schoolcraft County, Michigan. The objective was to assess the formulation’s compatibility with SLCP application procedures and equipment, and to determine its ability to deliver precise lampricide concentrations in a timely manner. SC was found to dilute easily with stream water and readily combined with TFM. As a result, target lampricide concentrations in the stream were achieved within 1 hour of initiating delivery. Moreover, concentrations remained within 9 percent of target values, with less than 2 percent variation across the width of the stream, demonstrating consistent and uniform distribution. These findings indicate that SC can support accurate and timely lampricide applications. When considered alongside previous research highlighting its favorable selectivity for sea lamprey and improved environmental safety, the results support the pursuit of registration and adoption of SC as a new tool for controlling invasive sea lamprey.

Publication Year 2026
Title Field performance evaluation of a bayluscide 20-percent suspension concentrate formulation
DOI 10.3133/ofr20261067
Authors Nadia Carmosini, Justin R. Schueller, Courtney A. Kirkeeng, Anne M. Wood, Lori A. Criger, James A. Luoma
Publication Type Report
Publication Subtype USGS Numbered Series
Series Title Open-File Report
Series Number 2026-1067
Index ID ofr20261067
Record Source USGS Publications Warehouse
USGS Organization Upper Midwest Environmental Sciences Center
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