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Serologic evidence of influenza A(H1N1)pdm09 virus in northern sea otters

April 7, 2014

Sporadic epizootics of pneumonia among marine mammals have been associated with multiple animal-origin influenza A virus subtypes (1–6); seals are the only known nonhuman host for influenza B viruses (7). Recently, we reported serologic evidence of influenza A virus infection in free-ranging northern sea otters (Enhydra lutris kenyoni) captured off the coast of Washington, USA, in August 2011 (8). To investigate further which influenza A virus subtype infected these otters, we tested serum samples from these otters by ELISA for antibody-binding activity against 12 recombinant hemagglutinins (rHAs) from 7 influenza A hemagglutinin (HA) subtypes and 2 lineages of influenza B virus (Technical Appendix Table 1). Estimated ages for the otters were 2–19 years (Technical Appendix Table 2); we also tested archived serum samples from sea otters of similar ages collected from a study conducted during 2001–2002 along the Washington coast (9).

Publication Year 2014
Title Serologic evidence of influenza A(H1N1)pdm09 virus in northern sea otters
DOI 10.3201/eid2005.131890
Authors Zhu-Nan Li, Hon S. Ip, Jessica F. Frost, C. LeAnn White, Michael J. Murray, Paul J. Carney, Xiang-Jie Sun, James Stevens, Min Z. Levine, Jacqueline M. Katz
Publication Type Article
Publication Subtype Journal Article
Series Title Emerging Infectious Diseases
Index ID 70100897
Record Source USGS Publications Warehouse
USGS Organization National Wildlife Health Center