Floristic and other vegetation data were collected at 3,175 sample sites to support land-cover mapping projects in Clark and Lincoln Counties, Nevada, from 2007 to 2013. Data were collected at sample sites that were selected to fulfill mapping priorities by one of two different plot sampling approaches. Samples were described at the stand level and classified into the National Vegetation Classification hierarchy at the alliance level and above. The vegetation database is presented in geospatial and tabular formats.