Keith A Loftin, Ph.D.
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A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans
The compound BMAA (β-N-methylamino-L-alanine) has been postulated to play a significant role in four serious neurological human diseases: Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) found on Guam, and ALS, Parkinsonism, and dementia that occur globally. ALS/PDC with symptoms of all three diseases first came to the attention of the scientific community during and...
Authors
Neil Chernoff, D. J. Hill, D. L. Diggs, B. D. Faison, B. M. Francis, J. R. Lang, M. M. Larue, T.-T. Le, Keith A. Loftin, J. N. Lugo, J. E. Schmid, W. W. Winnik
Cyanobacteria of the 2016 Lake Okeechobee and Okeechobee Waterway harmful algal bloom Cyanobacteria of the 2016 Lake Okeechobee and Okeechobee Waterway harmful algal bloom
The Lake Okeechobee and the Okeechobee Waterway (Lake Okeechobee, the St. Lucie Canal and River, and the Caloosahatchee River) experienced an extensive harmful algal bloom within Lake Okeechobee, the St. Lucie Canal and River and the Caloosahatchee River in 2016. In addition to the very visible bloom of the cyanobacterium Microcystis aeruginosa, several other cyanobacteria were present...
Authors
Barry H. Rosen, Timothy W. Davis, Christopher J. Gobler, Benjamin J. Kramer, Keith A. Loftin
Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in USA streams Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in USA streams
Surface water from 38 streams nationwide was assessed using 14 target-organic methods (719 compounds). Designed-bioactive anthropogenic contaminants (biocides, pharmaceuticals) comprised 57% of 406 organics detected at least once. The 10 most-frequently detected anthropogenic-organics included eight pesticides (desulfinylfipronil, AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIAT
Authors
Paul M. Bradley, Celeste A. Journey, Kristin M. Romanok, Larry B. Barber, Herbert T. Buxton, William T. Foreman, Edward T. Furlong, Susan T. Glassmeyer, Michelle L. Hladik, Luke R. Iwanowicz, Daniel K. Jones, Dana W. Kolpin, Kathryn M. Kuivila, Keith A. Loftin, Marc A. Mills, Michael T. Meyer, James L. Orlando, Timothy J. Reilly, Kelly L. Smalling, Daniel L. Villeneuve
Methods used to characterize the chemical composition and biological activity of environmental waters throughout the United States, 2012-14 Methods used to characterize the chemical composition and biological activity of environmental waters throughout the United States, 2012-14
A vast array of chemical compounds are in wide commercial use in the United States, and the potential ecological and human-health effect of exposure to chemical mixtures has been identified as a high priority in environment health science. Awareness of the potential effects of low-level chemical exposures is rising. The U.S. Geological Survey, in cooperation with the U.S. Environmental...
Authors
Kristin M. Romanok, Timothy J. Reilly, Larry B. Barber, J. Scott Boone, Herbert T. Buxton, William T. Foreman, Edward T. Furlong, Michelle Hladik, Luke R. Iwanowicz, Celeste A. Journey, Dana W. Kolpin, Kathryn Kuivila, Keith A. Loftin, Marc A. Mills, Michael T. Meyer, James L. Orlando, Kelly L. Smalling, Daniel L. Villeneuve, Paul M. Bradley
Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season
Glyphosate and atrazine are the most intensively used herbicides in the United States. Although there is abundant spatial and temporal information on atrazine occurrence at regional scales, there are far fewer data for glyphosate, and studies that compare the two herbicides are rare. We investigated temporal patterns in glyphosate and atrazine concentrations measured weekly during the...
Authors
Barbara Mahler, Peter C. Van Metre, Thomas E. Burley, Keith A. Loftin, Michael T. Meyer, Lisa H. Nowell
Water quality and bed sediment quality in the Albemarle Sound, North Carolina, 2012–14 Water quality and bed sediment quality in the Albemarle Sound, North Carolina, 2012–14
The Albemarle Sound region was selected in 2012 as one of two demonstration sites in the Nation to test and improve the design of the National Water Quality Monitoring Council’s National Monitoring Network (NMN) for U.S. Coastal Waters and Tributaries. The goal of the NMN for U.S. Coastal Waters and Tributaries is to provide information about the health of our oceans, coastal ecosystems...
Authors
Michelle C. Moorman, Sharon A. Fitzgerald, Laura N. Gurley, Ahmed Rhoni-Aref, Keith A. Loftin
Science and Products
Filter Total Items: 32
Filter Total Items: 28
No Result Found
Filter Total Items: 87
A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans
The compound BMAA (β-N-methylamino-L-alanine) has been postulated to play a significant role in four serious neurological human diseases: Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) found on Guam, and ALS, Parkinsonism, and dementia that occur globally. ALS/PDC with symptoms of all three diseases first came to the attention of the scientific community during and...
Authors
Neil Chernoff, D. J. Hill, D. L. Diggs, B. D. Faison, B. M. Francis, J. R. Lang, M. M. Larue, T.-T. Le, Keith A. Loftin, J. N. Lugo, J. E. Schmid, W. W. Winnik
Cyanobacteria of the 2016 Lake Okeechobee and Okeechobee Waterway harmful algal bloom Cyanobacteria of the 2016 Lake Okeechobee and Okeechobee Waterway harmful algal bloom
The Lake Okeechobee and the Okeechobee Waterway (Lake Okeechobee, the St. Lucie Canal and River, and the Caloosahatchee River) experienced an extensive harmful algal bloom within Lake Okeechobee, the St. Lucie Canal and River and the Caloosahatchee River in 2016. In addition to the very visible bloom of the cyanobacterium Microcystis aeruginosa, several other cyanobacteria were present...
Authors
Barry H. Rosen, Timothy W. Davis, Christopher J. Gobler, Benjamin J. Kramer, Keith A. Loftin
Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in USA streams Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in USA streams
Surface water from 38 streams nationwide was assessed using 14 target-organic methods (719 compounds). Designed-bioactive anthropogenic contaminants (biocides, pharmaceuticals) comprised 57% of 406 organics detected at least once. The 10 most-frequently detected anthropogenic-organics included eight pesticides (desulfinylfipronil, AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIAT
Authors
Paul M. Bradley, Celeste A. Journey, Kristin M. Romanok, Larry B. Barber, Herbert T. Buxton, William T. Foreman, Edward T. Furlong, Susan T. Glassmeyer, Michelle L. Hladik, Luke R. Iwanowicz, Daniel K. Jones, Dana W. Kolpin, Kathryn M. Kuivila, Keith A. Loftin, Marc A. Mills, Michael T. Meyer, James L. Orlando, Timothy J. Reilly, Kelly L. Smalling, Daniel L. Villeneuve
Methods used to characterize the chemical composition and biological activity of environmental waters throughout the United States, 2012-14 Methods used to characterize the chemical composition and biological activity of environmental waters throughout the United States, 2012-14
A vast array of chemical compounds are in wide commercial use in the United States, and the potential ecological and human-health effect of exposure to chemical mixtures has been identified as a high priority in environment health science. Awareness of the potential effects of low-level chemical exposures is rising. The U.S. Geological Survey, in cooperation with the U.S. Environmental...
Authors
Kristin M. Romanok, Timothy J. Reilly, Larry B. Barber, J. Scott Boone, Herbert T. Buxton, William T. Foreman, Edward T. Furlong, Michelle Hladik, Luke R. Iwanowicz, Celeste A. Journey, Dana W. Kolpin, Kathryn Kuivila, Keith A. Loftin, Marc A. Mills, Michael T. Meyer, James L. Orlando, Kelly L. Smalling, Daniel L. Villeneuve, Paul M. Bradley
Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season
Glyphosate and atrazine are the most intensively used herbicides in the United States. Although there is abundant spatial and temporal information on atrazine occurrence at regional scales, there are far fewer data for glyphosate, and studies that compare the two herbicides are rare. We investigated temporal patterns in glyphosate and atrazine concentrations measured weekly during the...
Authors
Barbara Mahler, Peter C. Van Metre, Thomas E. Burley, Keith A. Loftin, Michael T. Meyer, Lisa H. Nowell
Water quality and bed sediment quality in the Albemarle Sound, North Carolina, 2012–14 Water quality and bed sediment quality in the Albemarle Sound, North Carolina, 2012–14
The Albemarle Sound region was selected in 2012 as one of two demonstration sites in the Nation to test and improve the design of the National Water Quality Monitoring Council’s National Monitoring Network (NMN) for U.S. Coastal Waters and Tributaries. The goal of the NMN for U.S. Coastal Waters and Tributaries is to provide information about the health of our oceans, coastal ecosystems...
Authors
Michelle C. Moorman, Sharon A. Fitzgerald, Laura N. Gurley, Ahmed Rhoni-Aref, Keith A. Loftin