A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. "FD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
Snake fungal disease is an infectious disease confirmed in numerous species of snakes caused by the fungus Ophidiomyces ophidiicola.
Historically, reports of snakes with skin infections of unknown origin have been sporadic. Recently, the number of reported cases of skin infections in snakes has increased substantially. As of August 2017, the fungus Ophidiomyces ophidiicola has been detected in much of the eastern half of the U.S. However, researchers suspect that snake fungal disease (SFD) may be more widely distributed than these documented cases suggest, because efforts to monitor the health of many snake populations are limited. Snake fungal disease may also be underreported in populations where it affects snakes infrequently or in species that develop less severe illness.
Signs of SFD include localized thickening or crusting of the skin, ulcerated skin, nodules (that is, abnormal bumps) under the skin, abnormal molting, white opaque cloudiness of the eyes (not associated with molting), and facial disfiguration that can be quite severe, leading to emaciation and death. Many snake populations are already in decline and the recent emergence of SFD may accelerate this decline, causing certain species to disappear entirely from some locations.
In 2016 scientists from the National Wildlife Health Center (NWHC) published a study demonstrating that SFD is widespread in eastern North America, has a broad host range among snakes, and is the predominant cause of skin infections in wild snakes. The study also showed that O. ophiodiicola frequently causes non-lethal infections in snakes and that environmental changes are likely causing the recent emergence of severe and fatal infections in some snake populations. The NWHC has continued to participate in collaborative projects with multiple state natural resource agencies aimed at better understanding SFD and its potential impacts on snake populations. In support of this effort, the NWHC has analyzed samples from over 100 whole carcasses and biopsies from snakes exhibiting clinical signs consistent with SFD. The NWHC is working with researchers to better understand the epidemiology of SFD in different snake populations in North America and abroad. The intent of this research is to determine the spatial extent and severity of this disease in wild populations to determine if intervention is needed to reduce its impacts on sensitive populations.
We encourage conservation agencies and natural resource managers to contact the NWHC if snakes with clinical signs consistent with SFD are encountered.
For more information on snake fungal disease, see the USGS Fact Sheet: Snake fungal disease in North America: U.S. Geological Survey updates.
Below are images related to snake fungal disease.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. "FD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting several crusty ventral scales from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting several crusty ventral scales from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
An eastern rat snake (Pantherophis alleghaniensis) with opaque eyes and hard, crusty scales on its snout - telltale signs of snake fungal disease. (David Green, USGS)
An eastern rat snake (Pantherophis alleghaniensis) with opaque eyes and hard, crusty scales on its snout - telltale signs of snake fungal disease. (David Green, USGS)
Eastern rat snake (Pantherophis alleghaniensis) showing signs of fungal infection with crusting on lateral scales, captured in Passaic County, New Jersey, in March 2012 (case 23906).
Eastern rat snake (Pantherophis alleghaniensis) showing signs of fungal infection with crusting on lateral scales, captured in Passaic County, New Jersey, in March 2012 (case 23906).
Below are publications about snake fungal disease.
Snake fungal disease in North America: U.S. Geological Survey updates
Prevalence of Ophidiomyces ophidiicola and epizootiology of snake fungal disease in free-ranging Northern Pine Snakes (Pituophis melanoleucus melanoleucus) in New Jersey
A cross inoculation experiment reveals Ophidiomyces ophiodiicola and Nannizziopsis guarroi can each infect both snakes and lizards
Ophidiomycosis is related to seasonal patterns of reproduction, ecdysis, and thermoregulatory behavior in a free-living snake species
The population genetics of the causative agent of snake fungal disease indicate recent introductions to the USA
Soil reservoir dynamics of ophidiomyces ophidiicola, the causative agent of snake fungal disease
Effects of snake fungal disease on short‐term survival, behavior, and movement in free‐ranging snakes
Evidence of vertical transmission of the snake fungal pathogen Ophidiomyces ophiodiicola
Interactive effects of food supplementation and snake fungal disease on pregnant Pygmy Rattlesnakes and their offspring
Field diagnostics and seasonality of Ophidiomyces ophiodiicola in wild snake populations
Seasonal sex steroids indicate reproductive costs associated with snake fungal disease
Patterns of circulating corticosterone in a population of rattlesnakes afflicted with snake fungal disease: Stress hormones as a potential mediator of seasonal cycles in disease severity and outcomes
Snake fungal disease in North America: U.S. Geological Survey updates
Below are news stories about snake fungal disease.
Snake fungal disease is an infectious disease confirmed in numerous species of snakes caused by the fungus Ophidiomyces ophidiicola.
Historically, reports of snakes with skin infections of unknown origin have been sporadic. Recently, the number of reported cases of skin infections in snakes has increased substantially. As of August 2017, the fungus Ophidiomyces ophidiicola has been detected in much of the eastern half of the U.S. However, researchers suspect that snake fungal disease (SFD) may be more widely distributed than these documented cases suggest, because efforts to monitor the health of many snake populations are limited. Snake fungal disease may also be underreported in populations where it affects snakes infrequently or in species that develop less severe illness.
Signs of SFD include localized thickening or crusting of the skin, ulcerated skin, nodules (that is, abnormal bumps) under the skin, abnormal molting, white opaque cloudiness of the eyes (not associated with molting), and facial disfiguration that can be quite severe, leading to emaciation and death. Many snake populations are already in decline and the recent emergence of SFD may accelerate this decline, causing certain species to disappear entirely from some locations.
In 2016 scientists from the National Wildlife Health Center (NWHC) published a study demonstrating that SFD is widespread in eastern North America, has a broad host range among snakes, and is the predominant cause of skin infections in wild snakes. The study also showed that O. ophiodiicola frequently causes non-lethal infections in snakes and that environmental changes are likely causing the recent emergence of severe and fatal infections in some snake populations. The NWHC has continued to participate in collaborative projects with multiple state natural resource agencies aimed at better understanding SFD and its potential impacts on snake populations. In support of this effort, the NWHC has analyzed samples from over 100 whole carcasses and biopsies from snakes exhibiting clinical signs consistent with SFD. The NWHC is working with researchers to better understand the epidemiology of SFD in different snake populations in North America and abroad. The intent of this research is to determine the spatial extent and severity of this disease in wild populations to determine if intervention is needed to reduce its impacts on sensitive populations.
We encourage conservation agencies and natural resource managers to contact the NWHC if snakes with clinical signs consistent with SFD are encountered.
For more information on snake fungal disease, see the USGS Fact Sheet: Snake fungal disease in North America: U.S. Geological Survey updates.
Below are images related to snake fungal disease.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. "FD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. "FD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting several crusty ventral scales from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting several crusty ventral scales from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
A juvenile Broad-banded Watersnake that tested positive for snake fungal disease (SFD) exhibiting numerous nodules overlaid by roughened skin on the dorsal surface from St. Martin Parish, Louisiana. SFD has proven lethal in many snakes, and the disease is recognized as an emerging threat to wild snake populations.
An eastern rat snake (Pantherophis alleghaniensis) with opaque eyes and hard, crusty scales on its snout - telltale signs of snake fungal disease. (David Green, USGS)
An eastern rat snake (Pantherophis alleghaniensis) with opaque eyes and hard, crusty scales on its snout - telltale signs of snake fungal disease. (David Green, USGS)
Eastern rat snake (Pantherophis alleghaniensis) showing signs of fungal infection with crusting on lateral scales, captured in Passaic County, New Jersey, in March 2012 (case 23906).
Eastern rat snake (Pantherophis alleghaniensis) showing signs of fungal infection with crusting on lateral scales, captured in Passaic County, New Jersey, in March 2012 (case 23906).
Below are publications about snake fungal disease.
Snake fungal disease in North America: U.S. Geological Survey updates
Prevalence of Ophidiomyces ophidiicola and epizootiology of snake fungal disease in free-ranging Northern Pine Snakes (Pituophis melanoleucus melanoleucus) in New Jersey
A cross inoculation experiment reveals Ophidiomyces ophiodiicola and Nannizziopsis guarroi can each infect both snakes and lizards
Ophidiomycosis is related to seasonal patterns of reproduction, ecdysis, and thermoregulatory behavior in a free-living snake species
The population genetics of the causative agent of snake fungal disease indicate recent introductions to the USA
Soil reservoir dynamics of ophidiomyces ophidiicola, the causative agent of snake fungal disease
Effects of snake fungal disease on short‐term survival, behavior, and movement in free‐ranging snakes
Evidence of vertical transmission of the snake fungal pathogen Ophidiomyces ophiodiicola
Interactive effects of food supplementation and snake fungal disease on pregnant Pygmy Rattlesnakes and their offspring
Field diagnostics and seasonality of Ophidiomyces ophiodiicola in wild snake populations
Seasonal sex steroids indicate reproductive costs associated with snake fungal disease
Patterns of circulating corticosterone in a population of rattlesnakes afflicted with snake fungal disease: Stress hormones as a potential mediator of seasonal cycles in disease severity and outcomes
Snake fungal disease in North America: U.S. Geological Survey updates
Below are news stories about snake fungal disease.