Donald Tillitt, PhD (Former Employee)

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February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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Ecosystems Mission Area, Species Management Research Program, Columbia Environmental Research Center

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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January 1, 2007

Physical and hormonal examination of Missouri River shovelnose sturgeon reproductive stage: A reference guide Physical and hormonal examination of Missouri River shovelnose sturgeon reproductive stage: A reference guide

From May 2001 to June 2002 Wildhaber et al. (2005) conducted monthly sampling of Lower Missouri River shovelnose sturgeon (Scaphirhynchus platorynchus) to develop methods for determination of sex and the reproductive stage of sturgeons in the field. Shovelnose sturgeon were collected from the Missouri River and ultrasonic and endoscopic imagery and blood and gonadal tissue samples were...

Authors

M. L. Wildhaber, D. M. Papoulias, A. J. DeLonay, D. E. Tillitt, J.L. Bryan, M.L. Annis

By

Ecosystems Mission Area, Columbia Environmental Research Center

October 7, 2006

Biomonitoring of Environmental Status and Trends (BEST) Program: Environmental contaminants, health indicators, and reproductive biomarkers in fish from the Colorado River basin Biomonitoring of Environmental Status and Trends (BEST) Program: Environmental contaminants, health indicators, and reproductive biomarkers in fish from the Colorado River basin

Seven fish species were collected from 14 sites on rivers in the Colorado River Basin (CDRB) from August to October 2003. Spatial trends in the concentrations of accumulative contaminants were documented and contaminant effects on the fish were assessed. Sites were located on the mainstem of the Colorado River and on the Yampa, Green, Gunnison, San Juan, and Gila Rivers. Common carp...

Authors

Jo Ellen Hinck, Vicki Blazer, Nancy D. Denslow, Timothy S. Gross, Kathy R. Echols, Anne P. Davis, Tom W. May, Carl E. Orazio, James J. Coyle, Donald E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

July 1, 2006

Toxicogenomics in regulatory ecotoxicology Toxicogenomics in regulatory ecotoxicology

Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has...

Authors

Gerald T. Ankley, George P. Daston, Sigmund J. Degitz, Nancy D. Denslow, Robert A. Hoke, Sean W. Kennedy, Ann L. Miracle, Edward J. Perkins, Jason Snape, Donald E. Tillitt, Charles R. Tyler, Donald Versteeg

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Ecosystems Mission Area, Columbia Environmental Research Center

June 1, 2006

Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic

The effects of feeding ranch mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish (88 gold fish [Carassius auratus] weighing a total of 70.3 kg and 16 carp [Cyprinus carpio] weighing a total of 77.3 kg) collected from the Housatonic River (HR; Berkshire County, MA, USA) in October 1999 on organ weights and histology and hepatic concentrations of total...

Authors

Steven J. Bursian, Chanda Sharma, Richard J. Aulerich, Behzad Yamini, Rachel R. Mitchell, Kerrie J. Beckett, Carl E. Orazio, Dwayne Moore, Susan Svirsky, Donald E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

March 15, 2006

Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report

At the request of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, a subcommittee of the Board of Scientific Counselors Executive Committee conducted an independent and open peer review of the Endocrine Disrupting Chemicals Research Program (EDC Research Program) of the U.S. EPA. The subcommittee was charged with reviewing the design, relevance, progress

Authors

Anna K. Harding, George P. Daston, Glen R. Boyd, George W. Lucier, Stephen H. Safe, Juarine Stewart, Donald E. Tillitt, Glen Van Der Kraak

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2006

Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska

Organochlorine chemical residues and elemental contaminants were measured in northern pike (Esox lucius), longnose sucker (Catostomus catostomus), and burbot (Lota lota) from 10 sites in the Yukon River Basin (YRB) during 2002. Contaminant concentrations were compared to historical YRB data and to toxicity thresholds for fish and piscivorous wildlife from the scientific literature. A...

Authors

J.E. Hinck, C. J. Schmitt, K. R. Echols, T.W. May, C.E. Orazio, D. E. Tillitt

By

Columbia Environmental Research Center

January 1, 2006

Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival

We evaluated the effects of feeding farm-raised mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish from the Housatonic River (HR; Berkshire County, MA, USA) on adult reproductive performance and kit growth and survival. Diets contained 0.22-3.54% HR fish, providing 0.34-3.7 ??g total PCBs (TPCB)/g feed wet wt (3.5-68.5 pg toxic equivalence [TEQ]/g)...

Authors

S.J. Bursian, C. Sharma, R.J. Aulerich, B. Yamini, R.R. Mitchell, C.E. Orazio, D.R.J. Moore, S. Svirsky, D. E. Tillitt

By

Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2006

Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends

Fish were collected from 16 sites on rivers in the Columbia River Basin (CRB) from September 1997 to April 1998 to document temporal and spatial trends in the concentrations of accumulative contaminants and to assess contaminant effects on the fish. Sites were located on the mainstem of the Columbia River and on the Snake, Willamette, Yakima, Salmon, and Flathead Rivers. Common carp...

Authors

J.E. Hinck, C. J. Schmitt, V. S. Blazer, N. D. Denslow, T.M. Bartish, P.J. Anderson, J.J. Coyle, G.M. Dethloff, D. E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2006

Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River

Little is known about the reproductive biology of the exotic bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix in the Missouri River. In order to fill this gap in understanding, herein is described the reproductive condition of these Asian carps. Evidence is presented which indicates that bighead and silver carp in the Missouri River have a protracted...

Authors

D. M. Papoulias, D. Chapman, D. E. Tillitt

By

Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2005

Effect of sample handling on thiamine and thiaminolytic activity in alewife Effect of sample handling on thiamine and thiaminolytic activity in alewife

Alewives Alosa pseudoharengus were collected to evaluate handling and processing conditions that may affect the measurement of their thiamine-thiaminase content. Fish were captured by otter trawl, and reference samples of live fish were quick-frozen on dry ice immediately following capture. Other samples were placed on wet ice (4??C) or held in ambient lake water (21.5??C) for periods of...

Authors

G.M. Wright, S.B. Brown, L. R. Brown, K. Moore, M. Villella, J.L. Zajicek, D. E. Tillitt, J.D. Fitzsimons, D. C. Honeyfield

January 1, 2005

Can diet-dependent factors help explain fish-to-fish variation in thiamine-dependent early mortality syndrome? Can diet-dependent factors help explain fish-to-fish variation in thiamine-dependent early mortality syndrome?

To provide insight into the reasons why offspring of certain salmonine females exhibit early mortality syndrome (EMS) in the Great Lakes whereas others do not, we measured the egg concentrations of potential biochemical markers (stable isotopes of nitrogen and carbon, fatty acid signatures, and lipid-soluble carotenoids and vitamins) that are indicative of differing food web and trophic...

Authors

S.B. Brown, M.T. Arts, L. R. Brown, M. Brown, K. Moore, M. Villella, J.D. Fitzsimons, D. C. Honeyfield, D. E. Tillitt, J.L. Zajicek, M. Wolgamood, J.G. Hnath

By

Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2005

Effectiveness of egg immersion in aqueous solutions of thiamine and thiamine analogs for reducing early mortality syndrome Effectiveness of egg immersion in aqueous solutions of thiamine and thiamine analogs for reducing early mortality syndrome

Protocols used for therapeutic thiamine treatments in salmonine early mortality syndrome (EMS) were investigated in lake trout Salvelinus namaycush and coho salmon Oncorhynchus kisutch to assess their efficacy. At least 500 mg of thiamine HCl/L added to egg baths was required to produce a sustained elevation of thiamine content in lake trout eggs. Thiamine uptake from egg baths was not...

Authors

S.B. Brown, L. R. Brown, M. Brown, K. Moore, M. Villella, J.D. Fitzsimons, B. Williston, D. C. Honeyfield, J. P. Hinterkopf, D. E. Tillitt, J.L. Zajicek, M. Wolgamood

By

Ecosystems Mission Area, Columbia Environmental Research Center

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