Donald Tillitt, PhD (Former Employee)
Science and Products
Filter Total Items: 215
Toxicogenomics in regulatory ecotoxicology Toxicogenomics in regulatory ecotoxicology
Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has...
Authors
Gerald T. Ankley, George P. Daston, Sigmund J. Degitz, Nancy D. Denslow, Robert A. Hoke, Sean W. Kennedy, Ann L. Miracle, Edward J. Perkins, Jason Snape, Donald E. Tillitt, Charles R. Tyler, Donald Versteeg
Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic
The effects of feeding ranch mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish (88 gold fish [Carassius auratus] weighing a total of 70.3 kg and 16 carp [Cyprinus carpio] weighing a total of 77.3 kg) collected from the Housatonic River (HR; Berkshire County, MA, USA) in October 1999 on organ weights and histology and hepatic concentrations of total...
Authors
Steven J. Bursian, Chanda Sharma, Richard J. Aulerich, Behzad Yamini, Rachel R. Mitchell, Kerrie J. Beckett, Carl E. Orazio, Dwayne Moore, Susan Svirsky, Donald E. Tillitt
Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report
At the request of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, a subcommittee of the Board of Scientific Counselors Executive Committee conducted an independent and open peer review of the Endocrine Disrupting Chemicals Research Program (EDC Research Program) of the U.S. EPA. The subcommittee was charged with reviewing the design, relevance, progress
Authors
Anna K. Harding, George P. Daston, Glen R. Boyd, George W. Lucier, Stephen H. Safe, Juarine Stewart, Donald E. Tillitt, Glen Van Der Kraak
Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival
We evaluated the effects of feeding farm-raised mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish from the Housatonic River (HR; Berkshire County, MA, USA) on adult reproductive performance and kit growth and survival. Diets contained 0.22-3.54% HR fish, providing 0.34-3.7 ??g total PCBs (TPCB)/g feed wet wt (3.5-68.5 pg toxic equivalence [TEQ]/g)...
Authors
S.J. Bursian, C. Sharma, R.J. Aulerich, B. Yamini, R.R. Mitchell, C.E. Orazio, D.R.J. Moore, S. Svirsky, D. E. Tillitt
Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends
Fish were collected from 16 sites on rivers in the Columbia River Basin (CRB) from September 1997 to April 1998 to document temporal and spatial trends in the concentrations of accumulative contaminants and to assess contaminant effects on the fish. Sites were located on the mainstem of the Columbia River and on the Snake, Willamette, Yakima, Salmon, and Flathead Rivers. Common carp...
Authors
J.E. Hinck, C. J. Schmitt, V. S. Blazer, N. D. Denslow, T.M. Bartish, P.J. Anderson, J.J. Coyle, G.M. Dethloff, D. E. Tillitt
Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska
Organochlorine chemical residues and elemental contaminants were measured in northern pike (Esox lucius), longnose sucker (Catostomus catostomus), and burbot (Lota lota) from 10 sites in the Yukon River Basin (YRB) during 2002. Contaminant concentrations were compared to historical YRB data and to toxicity thresholds for fish and piscivorous wildlife from the scientific literature. A...
Authors
J.E. Hinck, C. J. Schmitt, K. R. Echols, T.W. May, C.E. Orazio, D. E. Tillitt
Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River
Little is known about the reproductive biology of the exotic bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix in the Missouri River. In order to fill this gap in understanding, herein is described the reproductive condition of these Asian carps. Evidence is presented which indicates that bighead and silver carp in the Missouri River have a protracted...
Authors
D. M. Papoulias, D. Chapman, D. E. Tillitt
Temporal and spatial variation of early mortality syndrome in salmonids from Lakes Michigan and Huron Temporal and spatial variation of early mortality syndrome in salmonids from Lakes Michigan and Huron
To assess the extent that early mortality syndrome (EMS) impacts different Pacific salmonid stocks and the association of EMS with thiamine, we collected eggs of coho salmon Oncorhynchus kisutch from three Lake Michigan tributaries (Platte River, Thompson Creek, and Root River) in 1996-2001. We also obtained eggs of Chinook salmon O. tshawytscha from Lake Michigan (Little Manistee River)...
Authors
M. Wolgamood, J.G. Hnath, S.B. Brown, K. Moore, S.V. Marcquenski, D. C. Honeyfield, J. P. Hinterkopf, J.D. Fitzsimons, D. E. Tillitt
Effect of sample handling on thiamine and thiaminolytic activity in alewife Effect of sample handling on thiamine and thiaminolytic activity in alewife
Alewives Alosa pseudoharengus were collected to evaluate handling and processing conditions that may affect the measurement of their thiamine-thiaminase content. Fish were captured by otter trawl, and reference samples of live fish were quick-frozen on dry ice immediately following capture. Other samples were placed on wet ice (4??C) or held in ambient lake water (21.5??C) for periods of...
Authors
G.M. Wright, S.B. Brown, L. R. Brown, K. Moore, M. Villella, J.L. Zajicek, D. E. Tillitt, J.D. Fitzsimons, D. C. Honeyfield
A rapid solid-phase extraction fluorometric method for thiamine and riboflavin in salmonid eggs A rapid solid-phase extraction fluorometric method for thiamine and riboflavin in salmonid eggs
A new method has been developed and successfully applied to the selective measurement of thiamine (nonphosphorylated), total thiamine (sum of thiamine, thiamine monophosphate [TMP], thiamine diphosphate [TDP], and thiamine triphosphate [TTP]), and potentially interfering riboflavin in acidic (2% trichloroacetic acid) extracts of selected salmonid and walleye egg samples. Acidic extracts...
Authors
James L. Zajicek, Donald E. Tillitt, Scott B. Brown, Lisa R. Brown, Dale C. Honeyfield, John D. Fitzsimons
A method for measuring total thiaminase activity in fish tissues A method for measuring total thiaminase activity in fish tissues
An accurate, quantitative, and rapid method for the measurement of thiaminase activity in fish samples is required to provide sufficient information to characterize the role of dietary thiaminase in the onset of thiamine deficiency in Great Lakes salmonines. A radiometric method that uses 14C-thiamine was optimized for substrate and co-substrate (nicotinic acid) concentrations...
Authors
James L. Zajicek, Donald E. Tillitt, Dale C. Honeyfield, Scott B. Brown, John D. Fitzsimons
Early mortality syndrome in Great Lakes salmonines Early mortality syndrome in Great Lakes salmonines
Early mortality syndrome (EMS) is the termused to describe an embryonic mortality affectingthe offspring of salmonines (coho salmonOnco-rhynchus kisutch, Chinook salmonOncorhynchustshawytscha, steelhead [anadromous rainbow troutOncorhynchus mykiss], brown troutSalmo trutta,and lake trout,Salvelinus namaycush) in LakesMichigan and Ontario and, to a lesser extent, LakesHuron and Erie...
Authors
Dale C. Honeyfield, Scott B. Brown, John D. Fitzsimons, Donald E. Tillitt
Science and Products
Filter Total Items: 215
Toxicogenomics in regulatory ecotoxicology Toxicogenomics in regulatory ecotoxicology
Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has...
Authors
Gerald T. Ankley, George P. Daston, Sigmund J. Degitz, Nancy D. Denslow, Robert A. Hoke, Sean W. Kennedy, Ann L. Miracle, Edward J. Perkins, Jason Snape, Donald E. Tillitt, Charles R. Tyler, Donald Versteeg
Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on organ weights and histology and hepatic concentrations of polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic
The effects of feeding ranch mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish (88 gold fish [Carassius auratus] weighing a total of 70.3 kg and 16 carp [Cyprinus carpio] weighing a total of 77.3 kg) collected from the Housatonic River (HR; Berkshire County, MA, USA) in October 1999 on organ weights and histology and hepatic concentrations of total...
Authors
Steven J. Bursian, Chanda Sharma, Richard J. Aulerich, Behzad Yamini, Rachel R. Mitchell, Kerrie J. Beckett, Carl E. Orazio, Dwayne Moore, Susan Svirsky, Donald E. Tillitt
Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report
At the request of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, a subcommittee of the Board of Scientific Counselors Executive Committee conducted an independent and open peer review of the Endocrine Disrupting Chemicals Research Program (EDC Research Program) of the U.S. EPA. The subcommittee was charged with reviewing the design, relevance, progress
Authors
Anna K. Harding, George P. Daston, Glen R. Boyd, George W. Lucier, Stephen H. Safe, Juarine Stewart, Donald E. Tillitt, Glen Van Der Kraak
Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival Dietary exposure of mink (Mustela vison) to fish from the Housatonic River, Berkshire County, Massachusetts, USA: Effects on reproduction, kit growth, and survival
We evaluated the effects of feeding farm-raised mink (Mustela vison) diets containing polychlorinated biphenyl (PCB)-contaminated fish from the Housatonic River (HR; Berkshire County, MA, USA) on adult reproductive performance and kit growth and survival. Diets contained 0.22-3.54% HR fish, providing 0.34-3.7 ??g total PCBs (TPCB)/g feed wet wt (3.5-68.5 pg toxic equivalence [TEQ]/g)...
Authors
S.J. Bursian, C. Sharma, R.J. Aulerich, B. Yamini, R.R. Mitchell, C.E. Orazio, D.R.J. Moore, S. Svirsky, D. E. Tillitt
Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends
Fish were collected from 16 sites on rivers in the Columbia River Basin (CRB) from September 1997 to April 1998 to document temporal and spatial trends in the concentrations of accumulative contaminants and to assess contaminant effects on the fish. Sites were located on the mainstem of the Columbia River and on the Snake, Willamette, Yakima, Salmon, and Flathead Rivers. Common carp...
Authors
J.E. Hinck, C. J. Schmitt, V. S. Blazer, N. D. Denslow, T.M. Bartish, P.J. Anderson, J.J. Coyle, G.M. Dethloff, D. E. Tillitt
Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska Environmental contaminants in fish and their associated risk to piscivorous wildlife in the Yukon River Basin, Alaska
Organochlorine chemical residues and elemental contaminants were measured in northern pike (Esox lucius), longnose sucker (Catostomus catostomus), and burbot (Lota lota) from 10 sites in the Yukon River Basin (YRB) during 2002. Contaminant concentrations were compared to historical YRB data and to toxicity thresholds for fish and piscivorous wildlife from the scientific literature. A...
Authors
J.E. Hinck, C. J. Schmitt, K. R. Echols, T.W. May, C.E. Orazio, D. E. Tillitt
Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River Reproductive condition and occurrence of intersex in bighead carp and silver carp in the Missouri River
Little is known about the reproductive biology of the exotic bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix in the Missouri River. In order to fill this gap in understanding, herein is described the reproductive condition of these Asian carps. Evidence is presented which indicates that bighead and silver carp in the Missouri River have a protracted...
Authors
D. M. Papoulias, D. Chapman, D. E. Tillitt
Temporal and spatial variation of early mortality syndrome in salmonids from Lakes Michigan and Huron Temporal and spatial variation of early mortality syndrome in salmonids from Lakes Michigan and Huron
To assess the extent that early mortality syndrome (EMS) impacts different Pacific salmonid stocks and the association of EMS with thiamine, we collected eggs of coho salmon Oncorhynchus kisutch from three Lake Michigan tributaries (Platte River, Thompson Creek, and Root River) in 1996-2001. We also obtained eggs of Chinook salmon O. tshawytscha from Lake Michigan (Little Manistee River)...
Authors
M. Wolgamood, J.G. Hnath, S.B. Brown, K. Moore, S.V. Marcquenski, D. C. Honeyfield, J. P. Hinterkopf, J.D. Fitzsimons, D. E. Tillitt
Effect of sample handling on thiamine and thiaminolytic activity in alewife Effect of sample handling on thiamine and thiaminolytic activity in alewife
Alewives Alosa pseudoharengus were collected to evaluate handling and processing conditions that may affect the measurement of their thiamine-thiaminase content. Fish were captured by otter trawl, and reference samples of live fish were quick-frozen on dry ice immediately following capture. Other samples were placed on wet ice (4??C) or held in ambient lake water (21.5??C) for periods of...
Authors
G.M. Wright, S.B. Brown, L. R. Brown, K. Moore, M. Villella, J.L. Zajicek, D. E. Tillitt, J.D. Fitzsimons, D. C. Honeyfield
A rapid solid-phase extraction fluorometric method for thiamine and riboflavin in salmonid eggs A rapid solid-phase extraction fluorometric method for thiamine and riboflavin in salmonid eggs
A new method has been developed and successfully applied to the selective measurement of thiamine (nonphosphorylated), total thiamine (sum of thiamine, thiamine monophosphate [TMP], thiamine diphosphate [TDP], and thiamine triphosphate [TTP]), and potentially interfering riboflavin in acidic (2% trichloroacetic acid) extracts of selected salmonid and walleye egg samples. Acidic extracts...
Authors
James L. Zajicek, Donald E. Tillitt, Scott B. Brown, Lisa R. Brown, Dale C. Honeyfield, John D. Fitzsimons
A method for measuring total thiaminase activity in fish tissues A method for measuring total thiaminase activity in fish tissues
An accurate, quantitative, and rapid method for the measurement of thiaminase activity in fish samples is required to provide sufficient information to characterize the role of dietary thiaminase in the onset of thiamine deficiency in Great Lakes salmonines. A radiometric method that uses 14C-thiamine was optimized for substrate and co-substrate (nicotinic acid) concentrations...
Authors
James L. Zajicek, Donald E. Tillitt, Dale C. Honeyfield, Scott B. Brown, John D. Fitzsimons
Early mortality syndrome in Great Lakes salmonines Early mortality syndrome in Great Lakes salmonines
Early mortality syndrome (EMS) is the termused to describe an embryonic mortality affectingthe offspring of salmonines (coho salmonOnco-rhynchus kisutch, Chinook salmonOncorhynchustshawytscha, steelhead [anadromous rainbow troutOncorhynchus mykiss], brown troutSalmo trutta,and lake trout,Salvelinus namaycush) in LakesMichigan and Ontario and, to a lesser extent, LakesHuron and Erie...
Authors
Dale C. Honeyfield, Scott B. Brown, John D. Fitzsimons, Donald E. Tillitt
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government