Donald Tillitt, PhD (Former Employee)

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February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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Ecosystems Mission Area, Species Management Research Program, Columbia Environmental Research Center

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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January 1, 2001

Accumulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rainbow trout (Onchorhynchus mykiss) at environmentally relevant dietary concentrations Accumulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rainbow trout (Onchorhynchus mykiss) at environmentally relevant dietary concentrations

Rainbow trout were fed a diet containing 1.8, 18, or 90 pg/g 3H-2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for up to 320 d. Concentrations of TCDD were determined in muscle, liver, and ovaries at 100, 150, 200, and 250 d. Concentrations of TCDD reached an apparent steady-state concentration in liver after 100 d of exposure, whereas concentrations in other tissues continued to increase...

Authors

Paul D. Jones, Kurunthachalam Kannan, John L. Newsted, Donald E. Tillitt, Lisa L. Williams, John P. Giesy

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2001

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos

Fundulus heteroclitus embryos were exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during early development using nanoinjection or water bath exposure. TCDD caused developmental abnormalities that included hemorrhaging, loss of vascular integrity, edema, stunted development and death. The LC50 and LD50 of TCDD for Fundulus embryos were ???19.7??9.5 pg TCDD/??l (water bath) and 0.25...

Authors

B.H. Toomey, S. Bello, M.E. Hahn, S. Cantrell, P. Wright, D. E. Tillitt, R.T. Di Giulio

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Ecosystems Mission Area, Columbia Environmental Research Center

November 30, 2000

Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure

This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish. A multitude of chemicals induce EROD activity in a variety of fish species, the most potent inducers being structural analogs of 2,3,7,8-tetracholordibenzo-p-dioxin...

Authors

J.J. Whyte, R.E. Jung, C. J. Schmitt, D. E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

July 13, 2000

PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin PCBs, liver lesions, and biomarker responses in adult walleye (Stizostedium vitreum vitreum) collected from Green Bay, Wisconsin

Adult walleye were collected from several locations in the Lower Fox River and Green Bay, Wisconsin (the assessment area) and two relatively uncontaminated reference locations (Lake Winnebago and Patten Lake, Wisconsin) between July and October in 1996 and 1997. Whole body and liver samples collected in 1996 were analyzed for total PCBs, PCB congeners, and liver histological lesions...

Authors

Mace G. Barron, Michael J. Anderson, Dave Cacela, Joshua Lipton, Swee J. Teh, David E. Hinton, Judith T. Zelikoff, Audrey L. Dikkeboom, Donald E. Tillitt, Mark Holey, Nancy Denslow

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2000

Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems Biomonitoring of Environmental Status and Trends (BEST) Program: Selected methods for monitoring chemical contaminants and their effects in aquatic ecosystems

This document describes the suite of biological methods of the U.S. Geological Survey- Biomonitoring of Environmental Status and Trends program for monitoring chemical contaminants and their effects on fish. The methods, which were selected by panels of experts, are being field-tested in rivers of the Mississippi River, Columbia River, and Rio Grande basins. General health biomarkers...

Authors

Vicki S. Blazer, Nancy D. Denslow, Gail M. Dethloff, Timothy S. Gross, Kelly K. McDonald, Christopher J. Schmitt, Donald E. Tillitt, Jeffrey J. Whyte

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Ecosystems Mission Area, Chesapeake Bay Activities, Columbia Environmental Research Center

January 1, 2000

Comparing polychlorinated biphenyl concentrations and patterns in the Saginaw River using sediment, caged fish, and semipermeable membrane devices Comparing polychlorinated biphenyl concentrations and patterns in the Saginaw River using sediment, caged fish, and semipermeable membrane devices

Three techniques of assessing bioavailable polychlorinated biphenyls (PCBs) in the Saginaw River, MI, were compared: sediments, caged fish, and semipermeable membrane devices (SPMDs). SPMDs and caged fish were placed in the river for 28 days at five sites where sediments were also sampled. The samples were analyzed for PCB congeners to determine concentrations and patterns. Total PCB

Authors

K. R. Echols, R.W. Gale, T.R. Schwartz, J.N. Huckins, L.L. Williams, J.C. Meadows, D. Morse, J. D. Petty, C.E. Orazio, D. E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2000

Progress and over-view of current GLFT EMS project: Report on Early Mortality Syndrome Workshop Progress and over-view of current GLFT EMS project: Report on Early Mortality Syndrome Workshop

No abstract available at this time

Authors

J. Fitzsimons, S.B. Brown, D. C. Honeyfield, D. E. Tillitt

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Ecosystems Mission Area, Eastern Ecological Science Center

January 1, 2000

Observed changes in early mortality syndrome in Lake Michigan coho and chinook salmon from 1994-1999 Observed changes in early mortality syndrome in Lake Michigan coho and chinook salmon from 1994-1999

No abstract available at this time

Authors

J. Hnath, M. Wolgamood, S.V. Marcquenski, S.B. Brown, J.D. Fitzsimons, D. E. Tillitt, D. C. Honeyfield

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Ecosystems Mission Area, Eastern Ecological Science Center

January 1, 2000

Dietary alewife and bloater chub effect on lake trout egg thiamine; Report on early mortality syndrome workshop Dietary alewife and bloater chub effect on lake trout egg thiamine; Report on early mortality syndrome workshop

No abstract available at this time

Authors

D. C. Honeyfield, J. P. Hinterkopf, J. Fitzsimons, S.B. Brown, D. E. Tillitt

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Ecosystems Mission Area, Eastern Ecological Science Center

January 1, 2000

Evaluation of planar halogenated and polycyclic aromatic hydrocarbons in estuarine sediments using ethoxyresorufin-O-deethylase induction of H4IIE cells Evaluation of planar halogenated and polycyclic aromatic hydrocarbons in estuarine sediments using ethoxyresorufin-O-deethylase induction of H4IIE cells

Polycyclic aromatic hydrocarbons (PAHs) and planar halogenated hydrocarbons (PHHs), including polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and biphenyls (PCBs) were determined in fractionated sediment extracts from the Hudson-Raritan estuary and Newark Bay, New Jersey, USA, as part of a comprehensive risk assessment. Contributions of PCDDs/PCDFs, PCBs, and PAHs to...

Authors

R.W. Gale, E.R. Long, T.R. Schwartz, D. E. Tillitt

January 1, 2000

Effects of methyl testosterone exposure on sexual differentiation in medaka, Oryzias latipes Effects of methyl testosterone exposure on sexual differentiation in medaka, Oryzias latipes

Studies were conducted to characterize effects of a known androgen on sexual differentiation and development of medaka, Oryzias latipes (d-rR strain), at two life stages. Embryos were injected with graded doses of methyl testosterone (MT) prior to epiboly. The occurrence of sex-reversal, and the gonadosomatic index (GSI) were evaluated in adults. Primary germ cells were counted and gonad...

Authors

D. M. Papoulias, Douglas B. Noltie, D. E. Tillitt

January 1, 2000

The 1995 and 1997 best projects The 1995 and 1997 best projects

No abstract available at this time

Authors

C. J. Schmitt, D. E. Tillitt, V. S. Blazer

By

Ecosystems Mission Area, Eastern Ecological Science Center

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